Degn, S. E., Jensen, L., Hansen, A. G., Duman, D., Tekin, M.
, Jensenius, J. C. & Thiel, S. (2012).
Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function.
Journal of Immunology,
189(8), 3957-69.
https://doi.org/10.4049/jimmunol.1201736
Østergaard, J. A., Bjerre, M., RamachandraRao, S. P., Sharma, A. K.
, Nyengaard, J. R., Hansen, T. K., Thiel, S. & Flyvbjerg, A. (2012).
Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model.
Experimental Diabetes Research,
2012, 678381.
https://doi.org/10.1155/2012/678381
Thiel, S., Jensen, L., Degn, S. E., Nielsen, H. J., Gál, P., Dobó, J.
& Jensenius, J. C. (2012).
Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.
Clinical and Experimental Immunology. Supplement,
169(1), 38-48.
https://doi.org/10.1111/j.1365-2249.2012.04584.x
Grönwall, C., Chen, Y., Vas, J., Khanna, S.
, Thiel, S., Corr, M., Kono, D. H. & Silverman, G. J. (2012).
MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses.
Proceedings of the National Academy of Sciences (PNAS),
109(48), 19745-50.
https://doi.org/10.1073/pnas.1211868109Foldager, L., Steffensen, R. N., Thiel, S., Als, T. D., Nielsen, H. J., Nordentoft, M.
, Mortensen, P. B., Mors, O. & Jensenius, J. C. (2012).
MBL and MASP-2 concentrations in serum and MBL2 promoter polymorphisms are associated to schizophrenia.
Acta Neuropsychiatrica,
24(4), 199-207.
https://doi.org/10.1111/j.1601-5215.2011.00618.x
Kjær, T. R., Hansen, A. G., Sørensen, U. B. S., Holm, A. T., Sørensen, G. L.
, Jensenius, J. C. & Thiel, S. (2012).
M-ficolin binds selectively to the capsular polysaccharides of Streptococcus pneumoniae serotypes 19B and 19C and of a S. mitis strain.
Infection and Immunity.
https://doi.org/10.1128/IAI.01148-12
Schlapbach, L. J.
, Kjær, T. R., Thiel, S., Mattmann, M., Nelle, M., Wagner, B. P., Ammann, R. A., Aebi, C.
& Jensenius, J. C. (2012).
M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis.
Pediatric Research,
71(4 Pt 1), 368-74.
https://doi.org/10.1038/pr.2011.71Ameye, L., Paesmans, M.
, Thiel, S., Jensenius, J. C. & Aoun, M. (2012).
M-ficolin levels are associated with the occurrence of severe infections in patients with haematological cancer undergoing chemotherapy.
Clinical and Experimental Immunology. Supplement,
167(2), 303-8.
https://doi.org/10.1111/j.1365-2249.2011.04512.xAmmitzbøll, C. G., Kjær, T. R., Steffensen, R., Stengaard-Pedersen, K., Nielsen, H. J., Thiel, S., Bøgsted, M. & Jensenius, J. C. (2012).
Non-Synonymous Polymorphisms in the FCN1 Gene Determine Ligand-Binding Ability and Serum Levels of M-Ficolin.
PLoS One,
7(11), e50585.
https://doi.org/10.1371/journal.pone.0050585
Kidmose, R. T., Laursen, N. S., Dobó, J.
, Kjaer, T. R., Sirotkina, S., Yatime, L., Sottrup-Jensen, L., Thiel, S., Gál, P.
& Andersen, G. R. (2012).
Structural basis for activation of the complement system by component C4 cleavage.
Proceedings of the National Academy of Sciences (PNAS),
109(38), 15425-15430.
https://doi.org/10.1073/pnas.1208031109
Høyem, P. H., Bruun, J. M., Pedersen, S. B., Thiel, S., Richelsen, B., Christiansen, J. S. & Hansen, T. K. (2012).
The effect of weight loss on serum mannose-binding lectin levels.
Clinical & Developmental Immunology,
2012, 354894.
https://doi.org/10.1155/2012/354894
Gjelstrup, L. C., Kaspersen, J. D., Behrens, M. A., Pedersen, J. S., Thiel, S., Kingshott, P., Oliveira, C. L. P., Thielens, N. M.
& Vorup-Jensen, T. (2012).
The role of nanometer-scaled ligand patterns in polyvalent binding by large mannan-binding lectin oligomers.
Journal of Immunology,
188(3), 1292-306.
https://doi.org/10.4049/jimmunol.1103012
Reichhardt, M. P., Loimaranta, V.
, Thiel, S., Finne, J., Meri, S. & Jarva, H. (2012).
The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces.
Frontiers in Immunology,
3, 205.
https://doi.org/10.3389/fimmu.2012.00205Degn, S. E., Andersen, S. H., Jensen, L., Thiel, S. & Jensenius, J. C. (2011).
Assay interference caused by antibodies reacting with rat kappa light-chain in human sera.
Journal of Immunological Methods,
372(1-2), 204-8.
https://doi.org/10.1016/j.jim.2011.06.030
Østergaard, J., Thiel, S., Hansen, T. K., Rasch, R. & Flyvbjerg, A. (2011).
Comment on: Lin et al. (2010) Immune Cell-Derived C3 Is Required for Autoimmune Diabetes Induced by Multiple Low Doses of Streptozotocin. Diabetes;59: 2247-2252.
Diabetes,
60(1), e7-8.
https://doi.org/10.2337/db10-1298
Clemons, K. V., Martinez, M., Axelsen, M.
, Thiel, S. & Stevens, D. (2011).
Efficacy of recombinant human mannose binding lectin alone and in combination with itraconazole against murine Candida albicans vaginitis.
Clinical Application of Immunological Investigations,
40(6), 553-68.
https://doi.org/10.3109/08820139.2011.569627Petersen, T., Møller-Larsen, A., Thiel, S., Brudek, T., Hansen, T. K. & Christensen, T. (2011).
Immune responses to human endogenous retroviruses are associated with disease activity in multiple sclerosis.. Poster session presented at 14th Annual ESCV Meeting, Madeira, Portugal.
Ovesen, T., Rickers, J., Jensen, J. M., Thiel, S. & Veirum, J. E. (2011).
Immunodeficiencies in children with chronic post tympanic otorrhoea.
Danish Medical Bulletin (Online),
58(7), A4282.
Petersen, T., Møller-Larsen, A., Thiel, S., Hansen, T. K., Ellermann-Eriksen, S., Brudek, T. & Christensen, T. (2011).
Innate and adaptive anti-viral immune responses in MS patients treated with interferon-beta.
Retrovirology,
8 (Suppl 1), A214.
Kjaer, T. R., Hansen, A. G., Sørensen, U. B. S., Nielsen, O.
, Thiel, S. & Jensenius, J. C. (2011).
Investigations on the pattern recognition molecule M-ficolin: quantitative aspects of bacterial binding and leukocyte association.
Journal of Leukocyte Biology,
90(3), 425-37.
https://doi.org/10.1189/jlb.0411201
Ammitzboll, C. G., Thiel, S., Ellingsen, T.
, Deleuran, B., Jorgensen, A., Jensenius, J. C. & Stengaard-Pedersen, K. (2011).
Levels of lectin pathway proteins in plasma and synovial fluid of rheumatoid arthritis and osteoarthritis.
Rheumatology International.
https://doi.org/10.1007/s00296-011-1879-x
Ytting, H., Christensen, I. J.
, Steffensen, R. N., Alsner, J., Thiel, S., Jensenius, J. C., Hansen, U. & Nielsen, H. J. (2011).
Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) genotypes in colorectal cancer.
Scandinavian Journal of Immunology,
73(2), 122-7.
https://doi.org/10.1111/j.1365-3083.2010.02480.xDegn, S. E., Thiel, S., Nielsen, O.
, Hansen, A. G., Steffensen, R. & Jensenius, J. C. (2011).
MAp19, the alternative splice product of the MASP2 gene.
Journal of Immunological Methods,
373(1-2), 89-101.
https://doi.org/10.1016/j.jim.2011.08.006
Boldt, A. B. W., Grisbach, C.
, Steffensen, R. N., Thiel, S., Kun, J. F. J.
, Jensenius, J. C. & Messias-Reason, I. J. T. (2011).
Multiplex sequence-specific polymerase chain reaction reveals new MASP2 haplotypes associated with MASP-2 and MAp19 serum levels.
Human Immunology,
72(9), 753-60.
https://doi.org/10.1016/j.humimm.2011.05.015Brinkmann, C. R., Thiel, S., Larsen, M. K., Petersen, T. E.
, Jensenius, J. C. & Heegaard, C. W. (2011).
Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human (alpha)-lactalbumin.
Journal of Dairy Science,
94(5), 2159-2170.
Brinkmann, C. R., Thiel, S., Larsen, M. K., Petersen, T. E., Jensenius, J. C. & Heegaard, C. W. (2011).
Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human α-lactalbumin.
Indian Journal of Dairy Science,
94(5), 2159-2170.
https://doi.org/10.3168/jds.2010-3622
Sallenbach, S.
, Thiel, S., Aebi, C., Otth, M., Bigler, S.
, Jensenius, J. C., Schlapbach, L. J. & Ammann, R. A. (2011).
Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2).
Pediatric Allergy and Immunology,
22(4), 424-30.
https://doi.org/10.1111/j.1399-3038.2010.01104.xGjelstrup, L. C., Andersen, S. H., Petersen, S. V., Enghild, J. J., Blom, A. M.
, Vorup-Jensen, T. & Thiel, S. (2011).
The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: the monoclonal antibody KIM185 to CD18 also binds C4-binding protein.
Molecular Immunology,
49(1-2), 38-47.
https://doi.org/10.1016/j.molimm.2011.07.018
Brinkmann, C. R., Heegaard, C. W., Petersen, T. E., Jensenius, J. C. & Thiel, S. (2011).
The toxicity of bovine α-lactalbumin made lethal to tumor cells is highly dependent on oleic acid and induces killing in cancer cell lines and noncancer-derived primary cells.
FEBS journal,
278(11), 1955-67.
https://doi.org/10.1111/j.1742-4658.2011.08112.x
Brinkmann, C. R., Thiel, S., Jensenius, J. C., Heegaard, C. W. & Petersen, T. E. (2010).
A complex of oleic acid and alpha lactalbumin induces cell death resembling either necrosis or apoptosis dependent on the type of cancer cell line. Poster session presented at The 7th European Workshop on Cell Death - Death among Vikings, Tisvildeleje, Denmark.
Degn, S. E., Jensen, L., Gál, P., Dobó, J., Holmvad, S. H.
, Jensenius, J. C. & Thiel, S. (2010).
Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system.
Journal of Immunological Methods,
361(1-2), 37-50.
https://doi.org/10.1016/j.jim.2010.07.006
Wittenborn, T., Thiel, S., Jensen, L., Nielsen, H. J. & Jensenius, J. C. (2010).
Characteristics and biological variations of M-ficolin, a pattern recognition molecule, in plasma.
Journal of Innate Immunity,
2(2), 167-80.
https://doi.org/10.1159/000218324
Schlapbach, L. J.
, Thiel, S., Kessler, U., Ammann, R. A., Aebi, C.
& Jensenius, J. C. (2010).
Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitis.
Gut.
https://doi.org/10.1136/gut.2010.226027Schlapbach, L. J., Mattmann, M.
, Thiel, S., Boillat, C., Otth, M., Nelle, M., Wagner, B.
, Jensenius, J. C. & Aebi, C. (2010).
Differential role of the lectin pathway of complement activation in susceptibility to neonatal sepsis.
Clinical Infectious Diseases,
51(2), 153-62.
https://doi.org/10.1086/653531Gjelstrup, L. C., Boesen, T., Kragstrup, T. W., Jørgensen, A., Klein, N. J.
, Thiel, S., Deleuran, B. W. & Vorup-Jensen, T. (2010).
Functionally Active CD11/CD18 Integrin Complexes are Shedded From the Leukocyte Membranes in Chronic Inflammation Disorders.
Scandinavian Journal of Immunology,
71(6), 515-515.
Chang, W.-C., White, M. R., Moyo, P., McClear, S.
, Thiel, S., Hartshorn, K. L. & Takahashi, K. (2010).
Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection.
BMC Immunology,
11, 64.
https://doi.org/10.1186/1471-2172-11-64Schlapbach, L. J.
, Thiel, S., Aebi, C., Hirt, A., Leibundgut, K.
, Jensenius, J. C. & Ammann, R. A. (2010).
M-ficolin in children with cancer.
Immunobiology.
https://doi.org/10.1016/j.imbio.2010.09.013Gjelstrup, L. C., Boesen, T., Kragstrup, T. W., Jørgensen, A., Klein, N. J.
, Thiel, S., Deleuran, B. & Vorup-Jensen, T. (2010).
Shedding of Large Functionally Active CD11/CD18 Integrin Complexes from Leukocyte Membranes during Synovial Inflammation Distinguishes Three Types of Arthritis through Differential Epitope Exposure.
Journal of Immunology,
185(7), 4154-68.
https://doi.org/10.4049/jimmunol.1000952
Brinkmann, C. R., Thiel, S., Jensenius, J. C., Heegaard, C. W. & Petersen, T. E. (2010).
BAMLET – cytotoxicity and an alternative preparation method . Poster session presented at 2
nd Symposium on HAMLET and tumor-killing proteins, Lund, Sweden.
Foldager, L., Steffensen, R. N., Thiel, S., Als, T. D., Kristensen, A. S., Straarup, S., Nielsen, H. J., Nordentoft, M.
, Mortensen, P. B., Rosenberg, R., Mors, O. & Jensenius, J. C. (2009).
Are defects in the innate immune defense contributing factors for mental disorders? In
PhD Day 2009 Abstract Book (pp. 107)
Foldager, L., Steffensen, R. N., Thiel, S., Als, T. D., Kristensen, A. S., Straarup, S., Nielsen, H. J., Nordentoft, M.
, Mortensen, P. B., Rosenberg, R., Mors, O. & Jensenius, J. C. (2009).
Are defects in the innate immune defense contributing factors for mental disorders?. Poster session presented at Ph.D. Day 2009, Århus, Denmark.
Chaouat, G., Petitbarat, M., Bulla, R., Dubanchet, S., Valdivia, K., Ledée, N.
, Steffen, T., Jensenius, J. C. & Tedesco, F. (2009).
Early regulators in abortion and implications for a preeclampsia model.
Journal of Reproductive Immunology,
82(2), 131-40.
https://doi.org/10.1016/j.jri.2009.08.004
