Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the Western world, encompassing a spectrum of liver damage. Multiple issues are involved on the cellular level in failing liver often involve enzyme deficiencies, such as reduced biosynthesis of S-adenosylmethionine (SAMe) or antioxidant properties. This project aims to coutneract the accumulation of reactive oxygen species (ROS) and reduced levels of glutathione (GSH). In healthy individuals, GSH is present in high levels in liver cells, playing a key role in removing ROS. In fatty liver cells, the missing antioxidant together with high ROS levels presents a toxic combination further pressuring the injured organ.