My research is deeply committed to unraveling the intricate relationship between brain hemodynamics and the energy demands of neuronal circuits, particularly in the context of neurodegenerative diseases, such as Alzheimer’s disease. A key dimension of my work involves understanding how early biological sex influences the development and progression of conditions such as Alzheimer’s disease, an area increasingly recognized for its clinical relevance yet still underexplored.
I investigate candidate drugs aimed at preventing microvascular disruption and enhancing brain oxygenation, applying advanced in-vivo optical imaging techniques such as two-photon microscopy, laser speckle imaging, and optogenetics, alongside molecular biology approaches. While my primary research is conducted in animal models, my training as a Medical Doctor provides a strong foundation for bridging basic science with clinical insight. This has allowed me to identify translational opportunities where preclinical findings can inform human disease mechanisms and potential interventions.
My goal is to contribute meaningfully to the understanding, treatment, and development of biomarkers for neurodegenerative diseases through a multidisciplinary and integrative lens.