Facility manager Nina Kølln Wittig and collegues just published a graphical review in Journal of Structural Biology highlighting opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging using AXIA infrastructure.
AXIA aims to build bridge between hospital CT and advanced synchrotron imaging, and while we have been able to conduct many synchrotron beamtimes remotely during corona lockdown, we were very excited to finally participate in X-ray diffraction-CT experiments on-site at the ID13 nanofocus beamline at the ESRF in Grenoble, France.
First measurements on our Xradia 620 Versa microscope have been conducted following basic training by a Zeiss specialist last week. These show great potential - for example we can resolve micrometer-sized osteocyte lacunae that are the negative imprint of a vast cellular network embedded within the mineralized bone tissue.
Our new state-of-the-art X-ray microscope, Xradia 620 Versa, has been delivered from the States and arrived at iNANO last week. The microscope is currently being installed by Zeiss experts and we expect to conduct the first measurements in a few weeks time.
As part of the AXIA initiative a SCANCO VivaCT 80 has been purchased and installed in the animal facilities at Dept. of Biomedicine at Aarhus University. The instrument allows for in vivo measurements of small animals with down to 10 µm image resolution. This is expected to lead to important new insights into the microstructural changes that occur during bone (re)modeling in growth, intervention, or disease.
