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Interdisciplinary Nanoscience Center

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Jørgen Kjems

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Liu, X., Howard, K. A., Dong, M., Andersen, M. Ø., Rahbek, U. L., Johnsen, M. G., Hansen, O. C., Besenbacher, F. & Kjems, J. (2007). The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. Biomaterials, 28(6), 1280-8. https://doi.org/10.1016/j.biomaterials.2006.11.004

Novotny, G. W., Sonne, S., Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebaek, N. E., Rajpert-De Meyts, E., Kjems, J. & Leffers, H. (2007). Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster. Cell Death and Differentiation, 14(4), 879-882. https://doi.org/10.1038/sj.cdd.4402090

Dong, M., Howard, K. A., Oupicky, D., Bisht, H. J., Kjems, J. & Besenbacher, F. (2007). Visualisation of Thermal Activated Nanocarriers Using In Situ Atomic Force Microscopy. Nanotechnology.

Dong, M. D., Howard, K. A., Oupicky, D., Bisht, H., Kjems, J. & Besenbacher, F. (2007). Visualization of thermally activated nanocarriers using in situ atomic force microscopy: Nanotechnology. Nanotechnology, 18(18), Article 185501. https://doi.org/10.1088/0957-4484/18/18/185501

Jonstrup, S. P., Koch, J. & Kjems, J. (2006). A microRNA detection system based on padlock probes and rolling circle amplification. RNA, 12(9), 1747-1752. https://doi.org/10.1261/rna.110706

Lützelberger, M., Reinert, L. S., Das, A. T., Berkhout, B. & Kjems, J. (2006). A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability. Journal of Biological Chemistry, 281(27), 18644-18651. https://doi.org/10.1074/jbc.M513698200

Mohey, R., Katzenstein, T. L., Black, F. T., Kjems, J. & Obel, N. (2006). Dynamics of proviral HIV-1 184M/V in circulating CD4+ T-cells: a 90 days follow-up study after initiation/switch of HAART. Scandinavian Journal of Infectious Diseases, 38(2), 119-123. https://doi.org/10.1080/00365540500348937

Mohey, R., Tolstrup, M., Jørgensen, L. B., Møller, B. K., Black, F. T., Kjems, J. & Obel, N. (2006). HIV-1 reverse Transcriptase Gene 103K/N and 184M/V Combinations in Tandem: Detection and Quantification of HIV-1 Populations in the CD45RO+ T-cell Compartment by a Double-ARMS Real-Time PCR assay. J A I D S, 41(2), 160-167. https://doi.org/10.1097/01.qai.0000191998.70034.64

Kjems, J., Liu, X., Howard, K. & Besenbacher, F. (2006). Nanoparticles for nuclear acid delivery.

Howard, K. A., Rahbek, U. L., Liu, X., Damgaard, C. K., Glud, S. Z., Andersen, M. Ø., Hovgaard, M. B., Schmitz, A., Nyengaard, J. R., Besenbacher, F. & Kjems, J. (2006). RNA interference in Vitro and in Vivo using a novel chitosan/siRNA nanoparticle system. Molecular Therapy, 14(4), 476-484. https://doi.org/10.1016/j.ymthe.2006.04.010

Birkedal, V., Krüger, A., Raarup, M. K., Kristensen, M., Kjems, J. & Besenbacher, F. (2006). Single molecule FRET microscopy on G-quadruplex DNA structures. Poster session presented at Single Molecule Picoquant Workshop, Berlin, Germany.

Krüger, A., Birkedal, V., Raarup, M. K., Kristensen, M., Kjems, J. & Besenbacher, F. (2006). Single-molecule Microscopy on Nucleic Acids. Poster session presented at NANOBIO Summer School "The live cell from nano to micro", Cargese, Corse, France.

Kjems, J. & Wengel, J. (2006). Small internally segmented interfering RNA.

Olesen, J. R., Kjems, J. & Besenbacher, F. (2006). Småt blir' godt: Nanomedicin i fremtidens sundhedssektor. Lægen i Midten, (5), 31.

Lützelberger, M. & Kjems, J. (2006). Strategies to identify potential therapeutic target sites in RNA. In V. Erdmann, J. Barciszewski & J. Brosius (Eds.), Handbook of Experimental Pharmacology: RNA Towards Medicine (Vol. 173, pp. 243-259). Springer. https://doi.org/10.1007/b138836

Paca-Uccaralertkun, S., Damgaard, C. K., Auewarakul, P., Thitithanyanont, A., Suphaphiphat, P., Essex, M., Kjems, J. & Lee, T.-H. (2006). The Effect of a Single Nucleotide Substitution in the Splicing Silencer in the tat/rev Intron on HIV Type 1 Envelope Expression. AIDS Research and Human Retroviruses, 22(1), 76-82. https://doi.org/10.1089/aid.2006.22.76

Kammler, S., Otte, M., Hauber, I., Kjems, J., Hauber, J. & Schaal, H. (2006). The strength of the HIV-1 3' splice sites affects Rev function. Retrovirology, 3(89), 1-20. https://doi.org/10.1186/1742-4690-3-89

Andersen, E. S. & Kjems, J. (2006). Virus er naturens selviske nanorobotter. In A.-L. S. Petersen & F. Besenbacher (Eds.), Nanoteknologi: 12 historier om den nyeste danske forskning (pp. 42-45).

Mukhopadhyay, R., Sumbayev, V. V., Lorentzen, M., Kjems, J., Andreasen, P. A. & Besenbacher, F. (2005). Cantilever sensor for nanomechanical detection of specific protein conformations. Nano Letters, 5(12), 2385-8. https://doi.org/10.1021/nl051449z

Mohey, R., Jørgensen, A. L., Møller, B. K., Black, F. T., Kjems, J. & Obel, N. (2005). Detection and quantification of proviral HIV-1 184 M/V in circulating CD4(+) T cells of patients on HAART with a viremia less than 1000 copies/ml. Journal of Clinical Virology, 34(4), 257-267. https://doi.org/10.1016/j.jcv.2005.02.015

Nielsen, M., Dauksaite, V., Kjems, J. & Gothelf, K. V. (2005). DNA-Directed Coupling of Organic Modules by Multiple Parallel Reductive Aminations and Subsequent Cleavage of Selected DNA Sequences. Bioconjugate Chem., 16(4), 981-985.

Kjems, J., Jakobsen, M. R. & Lützelberger, M. (2005). In vitro Selection Strategy to Identify Antisense Target Sites in RNA or hnRNP Complexes: Application on HIV-1.

Furnes, C., Arnesen, T., Askjaer, P., Kjems, J. & Szilvay, A. M. (2005). HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain. Retrovirology, 2, 39. https://doi.org/10.1186/1742-4690-2-39

Kjems, J., Bünger, C., Nygaard, J. V. & Mygind, T. (2005). Making implants last a lifetime. In iNANO Annual Report 2005 (pp. 14-15).

Nielsen, M. H., Pedersen, F. S. & Kjems, J. (2005). Molecular strategies to inhibit HIV-1 replication. Retrovirology, 2, 10. https://doi.org/10.1186/1742-4690-2-10

Mukhopadhyay, R., Lorentzen, M., Kjems, J. & Besenbacher, F. (2005). Nanomechanical sensing of DNA sequences using piezoresistive cantilevers. Langmuir, 21(18), 8400-8408. https://doi.org/10.1021/la0511687

Lützelberger, M., Jakobsen, M. R., Kjems, J., Hartmann, R. K. (Ed.), Schoen, A. (Ed.) & Westhof, E. (Ed.) (2005). SELEX Strategies to Identify Antisense and Protein Target Sites in RNA or Herogenous Nuclear Ribonucleoprotein Complexes. In Handbook of RNA Biochemistry (pp. 878-894). Wiley-VCH Verlag GmbH.

Krüger, A., Bukowy, Z., Lutzelberger, M., Stevnsner, T., Kristensen, M., Kjems, J., Besenbacher, F. & Raarup, M. K. (2005). Single-molecule FRET microscopy on DNA telomeres. Poster session presented at Bio-image summer school at ENS, Paris, France.

Jakobsen, M. R., Damgaard, C. K., Andersen, E. S., Podhajska, A. & Kjems, J. (2004). A genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNA. Nucleic Acids Research, 32(7), e67. https://doi.org/10.1093/nar/gnh064

Nygaard, J. V., Andersen, M. Ø., Howard, K., Sasov, A., Kjems, J. & Besenbacher, F. (2004). Analysis of Nanoparticles in Scaffolds for Tissue Engineering by use of X-Ray Nano Tomography. Poster session presented at iNANO 4^th annual meeting, Aarhus, Denmark.

Andersen, E. S., Kjems, J., Thostrup, P. & Besenbacher, F. (2004). Case study: HIVs hemmelige sexliv. Biozoom, 7(4), 23-25.

Knudsen, B., Andersen, E. S., Damgaard, C. K., Kjems, J. & Gorodkin, J. (2004). Evolutionary rate variation and RNA secondary structure prediction. Computational Biology and Chemistry, 28(3), 219-26. https://doi.org/10.1016/j.compbiolchem.2004.04.001

Damgaard, C. K., Andersen, E. S., Knudsen, B., Gorodkin, J. & Kjems, J. (2004). RNA interactions in the 5' region of the HIV-1 genome. Journal of Molecular Biology, 336(2), 369-79. https://doi.org/10.1016/j.jmb.2003.12.010

Andersen, E. S., Contera, S., Knudsen, B., Damgaard, C. K., Besenbacher, F. & Kjems, J. (2004). Role of the TAR hairpin in dimerization of HIV-1 RNA. Journal of Biological Chemistry, 279, 22243-22249.

Andersen, E. S., Contera, S. A., Knudsen, B., Damgaard, C. K., Besenbacher, F. & Kjems, J. (2004). Role of the trans-activation response element in dimerization of HIV-1 RNA. Journal of Biological Chemistry, 279(21), 22243-22249. https://doi.org/10.1074/jbc.M314326200

Zahler, A. M., Damgaard, C. K., Kjems, J. & Caputi, M. (2004). SC35 and heterogeneous nuclear ribonucleoprotein A/B proteins bind to a juxtaposed exonic splicing enhancer/exonic splicing silencer element to regulate HIV-1 tat exon 2 splicing. Journal of Biological Chemistry, 279(11), 10077-10084. https://doi.org/10.1074/jbc.M312743200

Zahler, A. M., Damgaard, C. K., Kjems, J. & Caputi, M. (2004). SC35 and hnRNPs A/B binding to a juxtaposed ESE/ESS element regulates HIV-1 tat exon 2 splicing. Journal of Biological Chemistry, 279, 10077-10084.

Freund, M., Asang, C., Kammler, S., Konermann, C., Krummheuer, J., Hipp, M., Meyer, I., Gierling, W., Theiss, S., Preuss, T., Schindler, D., Kjems, J. & Schaal, H. (2003). A novel approach to describe a U1 snRNA binding site. Nucleic Acids Research, 31(23), 6963-6975. https://doi.org/10.1093/nar/gkg901

Besenbacher, F., Kjems, J. & Andersen, E. S. (2003). Biomolekyler visualiseret med scanning probe mikroskopi. In Carlsberg Årsskrift 2003 (pp. 52-57)

Andersen, E. S., Jeeninga, R. E., Damgaard, C. K., Berkhout, B. & Kjems, J. (2003). Dimerization and template switching in the 5' untranslated region between various subtypes of human immunodeficiency virus type 1. Journal of Virology, 77(5), 3020-30. https://doi.org/10.1128/JVI.77.5.3020-3030.2003

Köster, M., Lykke-Andersen, S., Elnakady, Y. A., Gerth, K., Washausen, P., Höfle, G., Sasse, F., Kjems, J. & Hauser, H. (2003). Ratjadones inhibit nuclear export by blocking CRM1/exportin 1. Experimental Cell Research, 286(2), 321-331. https://doi.org/10.1016/S0014-4827(03)00100-9

Freund, M., Kammler, S., Krummheuer, J., Hipp, M., Meyer, I., Gierling, W., Theiss, S., Preuss, T., Kjems, J. & Schaal, H. (2003). The 5′ splice site consensus: hydrogen bonding pattern or nucleotide frequency? Nucl. Acid Res., 31, 6963-6975.

Andersen, F. F., Tange, T. Ø., Sinnathamby, T., Lohmann, J. S., Andersen, K. E., Kjems, J., Westergaard, O. & Knudsen, B. R. (2003). The RNA splicing factor ASF/SF2 inhibits human topoisomerase I mediated DNA relaxation. Poster session presented at Mechanisms of Eukaryotic Transcription, Cold Spring Harbor, United States.

Nielsen, K. B., Sinnathamby, T., Cartegni, L., Corydon, T. J., Kjems, J., Krainer, A. R., Elpeleg, O., Gregersen, N. & Andresen, B. S. (2003). A missense mutation found in patients with MCAD deficiency inactivates an exonic splicing enhancer in the MCAD gene. Poster session presented at Annual Meeting of the RNA society, Wien.

Lindtner, S., Felber, B. K. & Kjems, J. (2002). An element in the 3′untranslated region of human LINE-1 retrotransposon mRNA binds NXT1 (TAP) and can function as a nuclear export element. RNA, 8, 345-356.

Daelemans, D., Afonina, E., Nilsson, J., Werner, G., Kjems, J., Clercq, E., Pavlakis, G. N. & Vandamme, A. (2002). A novel inhibitor of the CRM-1 mediated pathway. Proceedings of the National Academy of Sciences (PNAS), 99, 14440-14445.

Lund, M. & Kjems, J. (2002). Defining a 5′ splice site by functional selection in the presence and absence of U1 snRNA 5′-end. RNA, 8, 166-179.

Damgaard, C. K., Tange, T. Ø. & Kjems, J. (2002). hnRNP A1 controls HIV-1 mRNA splicing through cooperative binding to intron and exon splicing silencers in the context of a conserved secondary structure. RNA, 8.

Dirac, A. M., Huthoff, H., Kjems, J. & Berkhout, B. (2002). Regulated HIV-2 RNA dimerization by means of alternative RNA conformation. Nucleic Acids Research, 30, 2647-2655.

A.M., D., H., H., Kjems, J. & B., B. (2002). Requirements for RNA-heterodimerization of the HIV-1 and HIV-2 genomes. Journal of General Virology, 83, 2533-2542.

Displaying results 351 to 400 out of 417

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Revised 17.04.2023

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Anne Færch Nielsen