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Interdisciplinary Nanoscience Center

CellPAT

Jørgen Kjems

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Schaffert, D. H., Okholm, A. H., Sørensen, R. S., Nielsen, J., Tørring, T., Rosen, C. B., Kodal, A. L. B., Mortensen, M. R., Gothelf, K. V. & Kjems, J. (2016). Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway. Small, 12(19), 2634-2640. https://doi.org/10.1002/smll.201503934

Sun, M., Chen, M., Wang, M., Hansen, J., Baatrup, A., Dagnæs-Hansen, F., Rölfing, J. D., Jensen, J., Lysdahl, H., Li, H., Johannsen, M., Le, D. Q. S., Kjems, J. & Bünger, C. (2016). In vivo drug release behavior and osseointegration of a doxorubicin-loaded tissue-engineered scaffold. RSC Advances, 6(80), 76237-76245. https://doi.org/10.1039/c6ra05351c

Svenningsen, K., Venø, M. T., Henningsen, K., Mallien, A. S., Jensen, L., Christensen, T., Kjems, J., Vollmayr, B. & Wiborg, O. (2016). MicroRNA Profiling in the Medial and Lateral Habenula of Rats Exposed to the Learned Helplessness Paradigm: Candidate Biomarkers for Susceptibility and Resilience to Inescapable Shock. PLOS ONE, 11(8), Article e0160318. https://doi.org/10.1371/journal.pone.0160318

Henshall, D. C., Hamer, H. M., Pasterkamp, R. J., Goldstein, D. B., Kjems, J., Prehn, J. H. M., Schorge, S., Lamottke, K. & Rosenow, F. (2016). MicroRNAs in epilepsy: pathophysiology and clinical utility. Lancet Neurology, 15(13), 1368-1376. http://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(16)30246-0.pdf

Martirosyan, A., Olesen, M. J., Fenton, R. A., Kjems, J. & Howard, K. A. (2016). Mucin-mediated nanocarrier disassembly for triggered uptake of oligonucleotides as a delivery strategy for the potential treatment of mucosal tumours. Nanoscale, 8(25), 12599-12607. https://doi.org/10.1039/c5nr07206a

Lou, C., Martos-Maldonado, M. C., Madsen, C. S., Thomsen, R. P., Midtgaard, S. R., Christensen, N. J., Kjems, J., Thulstrup, P. W., Wengel, J. & Jensen, K. J. (2016). Peptide-oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic. Nature Communications, 7, Article 12294. https://doi.org/10.1038/ncomms12294

Vu-Quang, H., Vinding, M. S., Nielsen, T., Ullisch, M. G., Nielsen, N. C. & Kjems, J. (2016). Theranostic Tumor Targeted Nanoparticles Combining Drug Delivery with Dual Near Infrared and (19)F Magnetic Resonance Imaging Modalities. Nanomedicine: Nanotechnology, Biology and Medicine, 12(7), 1873-1884. https://doi.org/10.1016/j.nano.2016.04.010

Sun, M., Wang, M., Chen, M., Dagnaes-Hansen, F., Le, D. Q. S., Baatrup, A., Horsman, M. R., Kjems, J. & Bünger, C. (2015). A tissue-engineered therapeutic device inhibits tumor growth in vitro and in vivo. Acta Biomaterialia, 18, 21-29. https://doi.org/10.1016/j.actbio.2015.02.004

Dupont, D. M., Larsen, N., Jensen, J. K., Andreasen, P. A. & Kjems, J. (2015). Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools. Nucleic Acids Research, 43(21), 1-13. Article e139. https://doi.org/10.1093/nar/gkv700

Song, W., Song, X., Yang, C., Gao, S., Klausen, L. H., Zhang, Y., Dong, M. & Kjems, J. (2015). Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion. International Journal of Nanomedicine (Online), 10, 2335-2346. https://doi.org/10.2147/IJN.S76513

Ebbesen, K., Kjems, J. & Hansen, T. B. (2015). Circular RNAs: Identification, biogenesis and function. Biochimica et Biophysica Acta, Gene Structure and Expression.

Chen, M., Andersen, M. Ø., Dillschneider, P., Chang, C.-C., Gao, S., Le, D. Q. S., Yang, C., Hein, S., Bünger, C. & Kjems, J. (2015). Co-delivery of siRNA and doxorubicin to cancer cells from additively manufactured implants. RSC Advances, 5, 101718-101725. https://doi.org/10.1039/C5RA23748C

Hansen, T. B., Venø, M. T., Damgaard, C. K. & Kjems, J. (2015). Comparison of circular RNA prediction tools. Nucleic Acids Research. https://doi.org/10.1093/nar/gkv1458

M. Zadegan, R., Jepsen, M. D. E., Hildebrandt, L., Birkedal, V. & Kjems, J. (2015). Construction of a fuzzy and all Boolean logic gates based on DNA. Small, 11(15), 1811-1817. https://doi.org/10.1002/smll.201402755

Jarczewska, M., Kekedy-Nagy, L., Nielsen, J. S., Campos, R., Kjems, J., Malinowska, E. & Ferapontova, E. E. (2015). Electroanalysis of pM-levels of urokinase plasminogen activator in serum by phosphorothioated RNA aptamer. Analyst, 140(11), 3794-3802. https://doi.org/10.1039/c4an02354d

Prabha, R., Kraft, D. C. E., Melsen, B., Varma, H., Nair, P. D., Kjems, J. & Kassem, M. (2015). Electrospun PVA-PCL-HAB scaffold for craniofacial bone regeneration. Tissue Engineering. Part A, 21(Supplement 1), S-58. https://doi.org/10.1089/ten.tea.2015.5000.abstracts

Sun, M., Yang, C., Zheng, J., Wang, M., Chen, M., Le, D. Q. S., Kjems, J. & Bünger, C. (2015). Enhanced efficacy of chemotherapy for breast cancer stem cells by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense. Acta Biomaterialia, 28, 171–182. https://doi.org/10.1016/j.actbio.2015.09.029

Sukosd, Z., Andersen, E. S., Seemann, S. E., Jensen, M., Hansen, M. B., Gorodkin, J. & Kjems, J. (2015). Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain. Nucleic Acids Research, 43(21), 10168-10179. https://doi.org/10.1093/nar/gkv1039

Chen, M., Le, D. Q. S., Kjems, J., Bünger, C. & Lysdahl, H. (2015). Improvement of distribution and osteogenic differentiation of human mesenchymal stem cells by hyaluronic acid and β-tricalcium phosphate-coated polymeric scaffold in vitro. BioResearch Open Access, 4(1), 363-373. https://doi.org/10.1089/biores.2015.0021

Sun, M., Chen, M., Wang, M., Hansen, J., Le, D. Q. S., Baatrup, A. O., Dagnaes-Hansen, F., Rölfing, J. H. D., Jensen, J., Lysdahl, H., Johannsen, M., Kjems, J. & Bünger, C. (2015). In Vivo Drug Release Behavior And Bone Biocompatibility Of Doxorubicin-loaded Tissueengineered Scaffold. #1994. Poster session presented at Orthopedic Research Society annual meeting 2015, Las Vegas, United States.

Ma, Z., Dagnaes-Hansen, F., Løvschall, H., Song, W., Nielsen, G. K., Yang, C., Wang, Q., Kjems, J. & Gao, S. (2015). Macrophage-mediated nanoparticle delivery to the periodontal lesions in established murine model via Pg-LPS induction. Journal of Oral Pathology & Medicine, 44(7), 538-542. https://doi.org/10.1111/jop.12269

Opazo, F., Eiden, L., Hansen, L., Rohrbach, F., Wengel, J., Kjems, J. & Mayer, G. (2015). Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer. Molecular Therapy - Nucleic Acids, 4, Article e251. https://doi.org/10.1038/mtna.2015.25

Okholm, A. H., Aslan, H., Besenbacher, F., Dong, MD. & Kjems, J. (2015). Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level. Nanoscale, 7(25), 10970-10973. https://doi.org/10.1039/c5nr01945a

Chang, C.-C., Chen, L., Venø, M. T., Kassem, M. & Kjems, J. (2015). Profiling Osteogenic microRNAs For RNAi-Functionalization Of Scaffolds In Bone Tissue Engineering. Poster session presented at NIH Symposium RNA Biology 2015, Maryland, United States.

Jiang, Z., Zhang, S., Yang, C., Kjems, J., Huang, Y., Besenbacher, F. & Dong, MD. (2015). Serum induced degradation of 3D DNA box origami observed by high speed atomic force microscope. Nano Research, 8(7), 2170-2178. https://doi.org/10.1007/s12274-015-0724-z

Jiang, Z., Zhang, S., Yang, C., Zadegan, R. M., Kjems, J., Huang, Y., Besenbacher, F. & Dong, M. (2015). Serum-induced degradation of 3D DNA box origami observed with high-speed atomic force microscopy (vol 8, pg 2170, 2015). Nano Research, 8(10), 3446-3446. https://doi.org/10.1007/s12274-015-0848-1

Jepsen, M. DE., Sørensen, R. S., Andersen, E. S., Kjems, J. & Birkedal, V. (2015). Single Molecule FRET Analysis of the Closed and Open States of a DNA Origami Box. Biophysical Journal, 108(2, suppl. 1), 175a. https://doi.org/10.1016/j.bpj.2014.11.968

Venø, M. T., Hansen, T. B., Venø, S. T., Clausen, B. H., Grebing, M., Finsen, B., Holm, I. E. & Kjems, J. (2015). Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development. Genome Biology, 16, Article 16:245. https://doi.org/10.1186/s13059-015-0801-3

Yang, C., Ogaki, R., Hansen, L., Kjems, J. & Mian Teo, B. (2015). Theranostic carbon dots derived from garlic with efficient anti-oxidative effects towards macrophages. R S C Advances, 118, 97836-97840. https://doi.org/10.1039/C5RA16874K

Yang, C., Thomsen, R. P., Ogaki, R., Kjems, J. & Mian Teo, B. (2015). Ultrastable green fluorescence carbon dots with a high quantum yield for bioimaging and use as theranostic carriers. Journal of Materials Chemistry B, 3(4577), 4577-4584. https://doi.org/10.1039/C5TB00467E

Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, N., Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, A. Y., Silahtaroglu, A., Kjems, J., Aronica, E. & Tümer, Z. (2014). Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance. Epilepsia, 55(12), 2017-2027. https://doi.org/10.1111/epi.12839

Wittenborn, T. R., Larsen, E. K. U., Nielsen, T., Rydtoft, L. M., Hansen, L., Nygaard, J. V., Vorup-Jensen, T., Kjems, J., Horsman, M. R. & Nielsen, N. C. (2014). Accumulation of nano-sized particles in a murine model of angiogenesis. Biochemical and Biophysical Research Communications, 443(2), 470-6. https://doi.org/10.1016/j.bbrc.2013.11.127

Nielsen, C., Kjems, J., Sorensen, K. R., Engelholm, L. H. & Behrendt, N. (2014). Advances in targeted delivery of small interfering RNA using simple bioconjugates. Expert Opinion on Drug Delivery, 11(5), 791-822. https://doi.org/10.1517/17425247.2014.896898

Ma, Z., Yang, C., Song, W., Wang, Q., Kjems, J. & Gao, S. (2014). Chitosan Hydrogel as siRNA vector for prolonged gene silencing. Journal of Nanobiotechnology, 12(23), 1-9. https://doi.org/10.1186/1477-3155-12-23

Yang, C., Nilsson, L., Cheema, M. U., Wang, Y., Frøkiær, J., Gao, S., Kjems, J. & Nørregaard, R. (2014). Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice. Theranostics, 5(2), 110-123. https://doi.org/10.7150/thno.9717

Song, J., Li, Q., Wang, X., Li, J., Zhang, S., Kjems, J., Besenbacher, F. & Dong, M. (2014). Evidence of Stranski-Krastanov growth at the initial stage of atmospheric water condensation. Nature Communications, 5, 1-8. Article 4837. https://doi.org/10.1038/ncomms5837

Okholm, A., Kjems, J. & Astakhova, K. (2014). Fluorescence detection of natural RNA using rationally designed "clickable" oligonucleotide probes. RSC Advances, 4(86), 45653-45656. https://doi.org/10.1039/c4ra07165d

Yang, C., Gao, S. & Kjems, J. (2014). Folic Acid Conjugated Chitosan for Targeted Delivery of siRNA to Activated Macrophages in vitro and in vivo. Journal of Materials Chemistry B, 48, 8608-8615. https://doi.org/10.1039/C4TB01374C

Cunyat, F., Beerens, N., Garcia, E., Clotet, B., Kjems, J. & Cabrera, C. (2014). Functional Analyses Reveal Extensive RRE Plasticity in Primary HIV-1 Sequences Selected under Selective Pressure. P L o S One, 9(8), Article 106299. https://doi.org/10.1371/journal.pone.0106299

Gao, S., Hein, S., Dagnæs-Hansen, F., Weyer, K., Yang, C., Nielsen, R., Christensen, E. I., Fenton, R. A. & Kjems, J. (2014). Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing. Theranostics, 4(10), 1039-51. https://doi.org/10.7150/thno.7866

Hansen, T. B., Venø, M. T., Kjems, J. & Damgaard, C. K. (2014). miRdentify: high stringency miRNA predictor identifies several novel animal miRNAs. Nucleic Acids Research, 42(16), 1-11. Article e124. https://doi.org/10.1093/nar/gku598

Kjems, J., Ferapontova, E. & Gothelf, K. V. (Eds.) (2014). Nucleic Acid Nanotechnology. Springer. Nucleic Acids and Molecular Biology Vol. 29 https://doi.org/10.1007/978-3-642-38815-6

Kjems, J., Ferapontova, E. & Gothelf, K. V. (2014). Preface. In J. Kjems, E. Ferapontova & K. V. Gothelf (Eds.), Nucleic Acid Nanotechnology (pp. ix-x). Springer.

Okholm, A. H., Nielsen, J. S., Vinther, M., Sørensen, R. S., Schaffert, D. & Kjems, J. (2014). Quantification of cellular uptake of DNA nanostructures by qPCR. Methods, 67(2), 193-197. https://doi.org/10.1016/j.ymeth.2014.01.013

Nawroth, I., Mueller, F., Basyuk, E., Beerens, N., Rahbek, U. L., Darzacq, X., Bertrand, E., Kjems, J. & Schmidt, U. (2014). Stable assembly of HIV-1 export complexes occurs cotranscriptionally. RNA, 20(1), 1-8. https://doi.org/10.1261/rna.038182.113

Sun, M., Wang, M., Chen, M., Dagnæs-Hansen, F., Le, D. Q. S., Baatrup, A., Horsman, M. R., Kjems, J. & Bünger, C. (2014). Sustained Drug Delivery Device for Treatment of Breast Cancer and Bone Metastases. #1167. Poster session presented at Orthopedic Research Society annual meeting 2014, New Orleans, United States.

Rosen, C. B., Kodal, A. L. B., Nielsen, J. S., Schaffert, D. H., Scavenius, C., Okholm, A. H., Voigt, N. V., Enghild, J. J., Kjems, J., Tørring, T. & Gothelf, K. V. (2014). Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins. Nature Chemistry, 6(9), 804-809. https://doi.org/10.1038/nchem.2003

Okholm, A. H., Schaffert, D. H. & Kjems, J. (2014). Towards Defined DNA and RNA Delivery Vehicles Using Nucleic Acid Nanotechnology. In Chemical Biology of Nucleic Acids (pp. 325-345). Springer. https://doi.org/10.1007/978-3-642-54452-1_18

Pedersen, L. H., Kellenberger, T., Yang, C., Gao, S., Kjems, J. & Wogensen, L. (2014). Treatment of Chronic Kidney Disease with Sirna Nanoparticles Targeting MMP-2. In Program and Abstract Book (pp. 158-158).

Dyrlund, T. F., Kirkegaard, K., Poulsen, E. T., Sanggaard, K. W., Hindkjær, J. J., Kjems, J., Enghild, J. J. & Ingerslev, H. J. (2014). Unconditioned commercial embryo culture media contain a large variety of non-declared proteins: a comprehensive proteomics analysis. Human Reproduction, 29(1), 2421-2430. https://doi.org/10.1093/humrep/deu220

Displaying results 151 to 200 out of 417

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Revised 17.04.2023

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Anne Færch Nielsen