STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Thiel, S. (2007). Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins. Molecular Immunology, 44(16), 3875-88. https://doi.org/10.1016/j.molimm.2007.06.005

Thiel, S. (1998). Plasma mannan-binding lectin kills microorganisms. Biomedicine & Pharmacotherapy, 52(1). https://doi.org/10.1016/S0753-3322(97)86243-9

Teillet, F., Lacroix, M., Thiel, S., Weilguny, D., Agger, T., Arlaud, GJ. & Thielens, NM. (2007). Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases: the essential role of Lys55. J. Immunol., 78, 5710-6.

Teillet, F., Lacroix, M., Thiel, S., Weilguny, D., Agger, T., Arlaud, G. J. & Thielens, N. M. (2007). Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases: the essential role of Lys55. Journal of Immunology, 178(9), 5710-6.

Tang, C., Kwiatkowski, D., Garred, P., Madsen, H. O., Svejgaard, A., Michaelsen, T. E., Hibberd, M. L., Sumiya, M., Summerfield, J. A., Booy, R., Levin, M., Van Helden, P., Hoal-van Helden, E., Kuijper, E. J., Fijen, C. A., Dankert, J., Thiel, S., Megyeri, P., Deli, M. A. & Abraham, C. S. (1999). Mannose-binding lectin and meningococcal disease (multiple letters) [3]. Lancet, 354(9175), 336-338. https://doi.org/10.1016/S0140-6736(05)75240-5

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Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark

Revised 08.12.2025

Rikke Ploug Frydenberg