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Interdisciplinary Nanoscience Center

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STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Stover, C. M., Schwaeble, W. J., Lynch, N. J., Thiel, S. & Speicher, M. R. (1999). Assignment of the gene encoding mannan-binding lectin-associated serine protease 2 (MASP2) to human chromosome 1p36.3-->p36.2 by in situ hybridization and somatic cell hybrid analysis. Cytogenetic and Genome Research, 84(3-4), 148-9.

Stover, C. M., Thiel, S., Thelen, M., Lynch, N. J., Vorup-Jensen, T., Jensenius, J. C. & Schwaeble, W. J. (1999). Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene. Journal of Immunology, 162(6), 3481-90.

Stover, C. M., Lynch, N. J., Dahl, M. R., Hanson, S. G., Takahashi, M., Frankenberger, M., Ziegler-Heitbrock, L., Eperon, I., Thiel, S. & Schwaeble, W. J. (2003). Murine serine proteases MASP-1 and MASP-3, components of the lectin pathway activation complex of complement, are encoded by a single structural gene. Genes and Immunity, 4(5), 374-84. https://doi.org/10.1038/sj.gene.6363970

Stover, C., Endo, Y., Takahashi, M., Lynch, N. J., Constantinescu, C., Vorup-Jensen, T., Thiel, S., Friedl, H., Hankeln, T., Hall, R., Gregory, S., Fujita, T. & Schwaeble, W. (2001). The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3. Genes and Immunity, 2(3), 119-27. https://doi.org/10.1038/sj.gene.6363745

Storm, L., Christensen, I. J., Jensenius, J. C., Nielsen, H. J., Thiel, S. & Danish Study Group on Early Detection of Colorectal Cancer (2015). Evaluation of complement proteins as screening markers for colorectal cancer. Cancer Immunology, Immunotherapy, 64(1), 41-50. https://doi.org/10.1007/s00262-014-1615-y

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Group leader

Postal Address

Interdisciplinary Nanoscience Center (iNANO)

Gustav Wieds Vej 14

8000 Aarhus C

Denmark

Revised 08.12.2025

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Rikke Ploug Frydenberg