Kidney diseases, atherosclerosis, colon cancer, non-alcoholic fatty liver disease and neurological disorders are five global health problems that the first five research projects in the Open Discovery Innovation Network (ODIN) are now addressing. In the projects, Ken Howard, Jørgen Kjems, and Daniel Otzen are among AU researchers and the pharmaceutical industry who are working together in full openness to generate new knowledge and new tools that can be used to develop new drugs.