Najarzadeh, Z., Mohammad-Beigi, H., Pedersen, J. N., Christiansen, G.
, Pedersen, J. S., Nielsen, J. & Otzen, D. E. (2022).
Interaction of membrane vesicles with the Pseudomonas functional amyloid protein FapC facilitates amyloid formation. BBA advances,
2, Article 100055.
https://doi.org/10.1016/j.bbadva.2022.100055
Nagaraj, M., Ahmed, M.
, Lyngsø, J., Vad, B. S., Bøggild, A., Fillipsen, A., Pedersen, J. S., Otzen, D. E. & Akbey, Ü. (2020).
Predicted Loop Regions Promote Aggregation: A Study of Amyloidogenic Domains in the Functional Amyloid FapC.
Journal of Molecular Biology,
432(7), 2232-2252.
https://doi.org/10.1016/j.jmb.2020.01.044
Nagaraj, M., Najarzadeh, Z., Pansieri, J., Biverstål, H., Musteikyte, G., Smirnovas, V., Matthews, S., Emanuelsson, C., Johansson, J., Buxbaum, J. N., Morozova-Roche, L.
& Otzen, D. E. (2022).
Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation.
Chemical Science,
13(2), 536-553.
https://doi.org/10.1039/d1sc05790a
Mortensen, H. G., Madsen, J. K., Andersen, K. K., Vosegaard, T., Deen, G. R.
, Otzen, D. E. & Pedersen, J. S. (2017).
Myoglobin and α-Lactalbumin Form Smaller Complexes with the Biosurfactant Rhamnolipid Than with SDS.
Biophysical Journal,
113(12), 2621-2633.
https://doi.org/10.1016/j.bpj.2017.10.024
Morgensen, JE., Ferreras, M., Wimmer, R.
, Petersen, S. V., Enghild, J. J. & Otzen, D. (2007).
The Major Allergen from Birch Tree Pollen, Bet v 1, Binds and Permeabilizes Membranes. Biochemistry.
Monti, M., Milanetti, E., Frans, M. T., Miotto, M., Di Rienzo, L., Baranov, M. V., Gosti, G.
, Somavarapu, A. K., Nagaraj, M., Golbek, T. W., Rossing, E., Moons, S. J., Boltje, T. J., van den Bogaart, G.
, Weidner, T., Otzen, D. E., Tartaglia, G. G., Ruocco, G.
& Roeters, S. J. (2024).
Two Receptor Binding Strategy of SARS-CoV-2 Is Mediated by Both the N-Terminal and Receptor-Binding Spike Domain.
The journal of physical chemistry. B,
128(2), 451-464.
https://doi.org/10.1021/acs.jpcb.3c06258
Mohammad-Beigi, H., Shojaosadati, S. A., Marvian, A. T.
, Pedersen, J. N., Klausen, L. H., Christiansen, G., Pedersen, J. S., Dong, M., Morshedi, D.
& Otzen, D. E. (2015).
Strong interactions with polyethylenimine-coated human serum albumin nanoparticles (PEI-HSA NPs) alter α-synuclein conformation and aggregation kinetics.
Nanoscale,
7, 19627-19640.
https://doi.org/10.1039/c5nr05663b
Mohammad-Beigi, H., Morshedi, D., Shojaosadati, S. A.
, Pedersen, J. N., Marvian, A. T., Aliakbari, F.
, Christiansen, G., Pedersen, J. S. & Otzen, D. E. (2016).
Gallic acid loaded onto polyethylenimine-coated human serum albumin nanoparticles (PEI-HSA-GA NPs) stabilizes α-synuclein in the unfolded conformation and inhibits aggregation.
RSC Advances,
6(88), 85312-85323.
https://doi.org/10.1039/c6ra08502d
Mohammad-Beigi, H., Aliakbari, F., Sahin, C., Lomax, C., Tawfike, A.
, P. Schafer, N., Amiri-Nowdijeh, A.
, Eskandari, H., Møller, I. M., Hosseini-Mazinani, M.
, Christiansen, G., Ward, J. L., Morshedi, D.
& Otzen, D. (2019).
Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity.
Journal of Biological Chemistry,
294(11), 4215-4232.
https://doi.org/10.1074/jbc.RA118.005723
Mohammad-Beigi, H., Kjær, L., Eskandari, H., Aliakbari, F., Christiansen, G., Ruvo, G., L. Ward, J.
& Otzen, D. (2019).
A Possible Connection Between Plant Longevity and the Absence of Protein Fibrillation: Basis for Identifying Aggregation Inhibitors in Plants.
Frontiers in Plant Science,
10(148), Article 148.
https://doi.org/10.3389/fpls.2019.00148
Mohammad-Beigi, H., Hosseini, A., Adeli, M., Ejtehadi, M. R.
, Christiansen, G., Sahin, C., Tu, Z., Tavakol, M., Dilmaghani-Marand, A., Nabipour, I., Farzadfar, F.
, Otzen, D. E., Mahmoudi, M. & Hajipour, M. J. (2019).
Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein.
ACS Nano,
13(3), 3243-3256.
https://doi.org/10.1021/acsnano.8b08983
Mohammad-Beigi, H., Zanganeh, M.
, Scavenius, C., Eskandari, H., Farzadfard, A., Shojaosadati, S. A.
, Enghild, J. J., Otzen, D. E., Buell, A. K.
& Sutherland, D. S. (2022).
A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation.
ACS Nano,
16(1), 1102-1118.
https://doi.org/10.1021/acsnano.1c08825
Mogensen, J. E., Wimmer, R., Larsen, J. N., Spangfort, M. D.
& Otzen, D. E. (2002).
The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands.
Journal of Biological Chemistry,
277(26), 23684-23692.
https://doi.org/10.1074/jbc.M202065200
Minero, G. A. S., Møllebjerg, A., Thiesen, C., Johansen, M. I., Jørgensen, N. P., Birkedal, V., Otzen, D. E. & Meyer, R. L. (2024).
Extracellular G-quadruplexes and Z-DNA protect biofilms from DNase I, and G-quadruplexes form a DNAzyme with peroxidase activity.
Nucleic Acids Research,
52(4), 1575-1590.
https://doi.org/10.1093/nar/gkae034
Milanetti, E., Miotto, M., Di Rienzo, L.
, Nagaraj, M., Monti, M.
, Golbek, T. W., Gosti, G.
, Roeters, S. J., Weidner, T., Otzen, D. E. & Ruocco, G. (2021).
In-Silico Evidence for a Two Receptor Based Strategy of SARS-CoV-2.
Frontiers in Molecular Biosciences,
8, Article 690655.
https://doi.org/10.3389/fmolb.2021.690655
Michaels, T. C. T., Yde, P., Willis, J. C. W., Jensen, M. H.
, Otzen, D., Dobson, C. M., Buell, A. K. & Knowles, T. P. J. (2015).
The length distribution of frangible biofilaments.
Journal of Chemical Physics,
143(16), 1-15. Article 164901.
https://doi.org/10.1063/1.4933230
Melo, E. P., Chen, L. Y., Cabral, J. M. S., Fojan, P.
, Petersen, S. B. & Otzen, D. E. (2003).
Trehalose favors a cutinase compact intermediate off-folding pathway.
Biochemistry,
42(24), 7611-7617.
https://doi.org/10.1021/bi034267x
Meisl, G., Xu, C. K., Taylor, J. D., Michaels, T. C. T., Levin, A.
, Otzen, D., Klenerman, D., Matthews, S., Linse, S.
, Andreasen, M. & Knowles, T. P. J. (2022).
Uncovering the universality of self-replication in protein aggregation and its link to disease.
Science Advances,
8(32), Article eabn6831.
https://doi.org/10.1126/sciadv.abn6831
Matouschek, A.
, Otzen, D. E., Itzhaki, L. S., Jackson, S. E. & Fersht, A. R. (1995).
Movement of the Position of the Transition State in Protein Folding.
Biochemistry,
34(41), 13656-13662.
https://doi.org/10.1021/bi00041a047
Marvian, A. T.
, Aliakbari, F., Mohammad-Beigi, H., Ahmadi, Z. A., Mehrpouyan, S., Lermyte, F., Nasouti, M., Collingwood, J. F.
, Otzen, D. E. & Morshedi, D. (2020).
The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization.
International Journal of Biological Macromolecules,
155, 543-550.
https://doi.org/10.1016/j.ijbiomac.2020.03.238
Martins, P. M., Navarro, S., Silva, A., Pinto, M. F., Sárkány, Z., Figueiredo, F., Pereira, P. J. B., Pinheiro, F., Bednarikova, Z., Burdukiewicz, M., Galzitskaya, O. V., Gazova, Z., Gomes, C. M., Pastore, A., Serpell, L. C., Skrabana, R., Smirnovas, V., Ziaunys, M.
, Otzen, D. E. ... Macedo-Ribeiro, S. (2020).
MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments.
Frontiers in Molecular Neuroscience,
13, Article 582488.
https://doi.org/10.3389/fnmol.2020.582488
Malmos, K. G., Bjerring, M., Jessen, C. M., Nielsen, E. H. T., Poulsen, E. T., Christiansen, G., Vosegaard, T., Skrydstrup, T., Enghild, J. J., Pedersen, J. S. & Otzen, D. E. (2016).
How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin.
Journal of Biological Chemistry,
291(32), 16849-16862.
https://doi.org/10.1074/jbc.M116.715466
Malmos, K., Blancas-Mejia, L. M., Weber, B., Buchner, J., Ramirez-Alvarado, M., Naiki, H.
& Otzen, D. (2017).
ThT 101: a primer on the use of thioflavin T to investigate amyloid formation.
Amyloid: the Journal of Protein Folding Disorders,
24(1), 1-16.
https://doi.org/10.1080/13506129.2017.1304905
Malmos, K. G., Stenvang, M., Sahin, C., Christiansen, G. & Otzen, D. E. (2017).
The Changing Face of Aging: Highly Sulfated Glycosaminoglycans Induce Amyloid Formation in a Lattice Corneal Dystrophy Model Protein.
Journal of Molecular Biology,
429(18), 2755-2764.
https://doi.org/10.1016/j.jmb.2017.07.014
Malmos, K. G., Bjerring, M., Jessen, C. M., Nielsen, E. H. T., Poulsen, E. T., Christiansen, G., Vosegaard, T., Skrydstrup, T., Enghild, J. J., Pedersen, J. S. & Otzen, D. E. (2017).
Correction to: How glycosaminoglycans promote fibrillation of salmon calcitonin.
Journal of Biological Chemistry,
292(38), 15992.
https://doi.org/10.1074/jbc.A116.715466
Madsen, J., Pihl, R., Møller, A. H., Tranberg Madsen, A., Otzen, D. & Andersen, K. K. (2015).
The anionic biosurfactant rhamnolipid does not denature industrial enzymes.
Frontiers in Microbiology,
6, Article 292.
https://doi.org/10.3389/fmicb.2015.00292
Madsen, J., Sørensen, T. R.
, Kaspersen, J. D., Silow, M. B., Vind, J.
, Pedersen, J. S., Svendsen, A.
& Otzen, D. E. (2015).
Promoting protein self-association in non-glycosylated Thermomyces lanuginosus lipase based on crystal lattice contacts.
BBA Proteins and Proteomics,
154(12), 1914-1921.
https://doi.org/10.1016/j.bbapap.2015.09.007
Madsen, J. L. H., Hjørringgaard, C. U., Vad, B. S., Otzen, D. & Skrydstrup, T. (2016).
Incorporation of β-Silicon-β3-Amino Acids in the Antimicrobial Peptide Alamethicin Provides a 20-Fold Increase in Membrane Permeabilization.
Chemistry: A European Journal,
22(24), 8358-8367.
https://doi.org/10.1002/chem.201600445
Madsen, J. K., Kaspersen, J. D., Andersen, K. K., Pedersen, J. S. & Otzen, D. E. (2016).
When Enzymes and Green Surfactants Meet.
Biophysical Journal,
110(3), 211A.
https://doi.org/10.1016/j.bpj.2015.11.1171
Madsen, J. K., Kaspersen, J. D., Andersen, C. B., Nedergaard Pedersen, J., Andersen, K. K., Pedersen, J. S. & Otzen, D. E. (2017).
Glycolipid Biosurfactants Activate, Dimerize, and Stabilize Thermomyces lanuginosus Lipase in a pH-Dependent Fashion.
Biochemistry,
56(32), 4256-4268.
https://doi.org/10.1021/acs.biochem.7b00420
Macchi, F., Hoffmann, S. V., Carlsen, M.
, Vad, B. S., Imparato, A., Rischel, C.
& Otzen, D. (2011).
Mechanical stress affects glucagon fibrillation kinetics and fibril structure.
Langmuir,
27(20), 12539–12549.
https://doi.org/10.1021/la202125c
Lorenzen, N., Cohen, S. I. A.
, Nielsen, S. B., Herling, T. W.
, Christiansen, G., Dobson, C. M., T. P. Knowles, T.
& Otzen, D. (2012).
Role of elongation and secondary pathways in S6 amyloid fibril growth.
Biophysical Journal,
102(9), 2167-2175.
https://doi.org/10.1016/j.bpj.2012.03.047
Lorenzen, N., Nielsen, S. B., Buell, A. K.
, Kaspersen, J. D., Arosio, P.
, Vad, B. S., Paslawski, W., Christiansen, G., Valnickova Hansen, Z., Andreasen, M., Enghild, J. J., Pedersen, J. S., Dobson, C. M., Knowles, T. P. J.
& Otzen, D. (2014).
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.
Journal of the American Chemical Society,
136(10), 3859-3868.
https://doi.org/10.1021/ja411577t
Lorenzen, N., Lemminger, L., Pedersen, J. N., Nielsen, S. B. & Otzen, D. (2014).
The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes.
FEBS Letters,
588(3), 497-502.
https://doi.org/10.1016/j.febslet.2013.12.015
Lorenzen, N., Nielsen, S. B., Yoshimura, Y., Vad, B. S., Andersen, C. B., Betzer, C., Kaspersen, J. D., Christiansen, G., Pedersen, J. S., Jensen, P. H., Mulder, F. A. A. & Otzen, D. E. (2014).
How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro.
Journal of Biological Chemistry,
289(31), 21299-21310.
https://doi.org/10.1074/jbc.M114.554667
Lopes, P., Dyrnesli, H.
, Lorenzen, N., Otzen, D. & Ferapontova, E. (2014).
Electrochemical Analysis of the Fibrillation of Parkinson's Disease α-synuclein.
Analyst,
139(4), 749-756.
https://doi.org/10.1039/C3AN01616A