Lassen, T. R., Just, J., Hjortbak, M. V., Jespersen, N. R., Stenz, K. T., Gu, T., Yan, Y., Su, J., Hansen, J., Bæk, R., Jørgensen, M. M., Nyengaard, J. R., Kristiansen, S. B., Drasbek, K. R., Kjems, J. & Bøtker, H. E. (2021). Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles. Basic Research in Cardiology, 116(1), Article 16. https://doi.org/10.1007/s00395-021-00856-w

Moldovan, L. I., Tsoi, L. C., Ranjitha, U., Hager, H., Weidinger, S., Gudjonsson, J. E., Kjems, J. & Kristensen, L. S. (2021). Characterization of Circular RNA Transcriptomes in Psoriasis and Atopic Dermatitis Reveals Disease-specific Expression Profiles. Experimental Dermatology, 30(8), 1187-1196. https://doi.org/10.1111/exd.14227

Yan, Y., Gu, T., Christensen, S. D. K., Su, J., Lassen, T. R., Hjortbak, M. V., Lo, I., Venø, S. T., Tóth, A. E., Song, P., Nielsen, M. S., Bøtker, H. E., Blagoev, B., Drasbek, K. R. & Kjems, J. (2021). Cyclic hypoxia conditioning alters the content of myoblast-derived extracellular vesicles and enhances their cell-protective functions. Biomedicines, 9(9), Article 1211. https://doi.org/10.3390/biomedicines9091211

Ahmadov, U., Bendikas, M. M., Ebbesen, K. K., Sehested, A. M., Kjems, J., Broholm, H. & Kristensen, L. S. (2021). Distinct circular RNA expression profiles in pediatric ependymomas. Brain Pathology, 31(2), 387-392. https://doi.org/10.1111/bpa.12922

Gomes-Duarte, A., Bauer, S., Venø, M. T., Norwood, B. A., Henshall, D. C., Kjems, J., Rosenow, F., Vangoor, V. R. & Pasterkamp, R. J. (2021). Enrichment of Circular RNA Expression Deregulation at the Transition to Recurrent Spontaneous Seizures in Experimental Temporal Lobe Epilepsy. Frontiers in Genetics, 12, Article 627907. https://doi.org/10.3389/fgene.2021.627907

Jakobsen, T., Dahl, M., Dimopoulos, K., Grønbæk, K., Kjems, J. & Kristensen, L. S. (2021). Genome-wide circular RNA expression patterns reflect resistance to immunomodulatory drugs in multiple myeloma cells. Cancers, 13(3), Article 365. https://doi.org/10.3390/cancers13030365

Krissanaprasit, A., Key, C. M., Froehlich, K., Pontula, S., Mihalko, E., Dupont, D. M., Andersen, E. S., Kjems, J., Brown, A. C. & LaBean, T. H. (2021). Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents. Advanced Healthcare Materials, 10(11), Article 2001826. https://doi.org/10.1002/adhm.202001826

Rahimi, K., Færch Nielsen, A., Venø, M. T. & Kjems, J. (2021). Nanopore long-read sequencing of circRNAs. Methods, 196, 23-29. https://doi.org/10.1016/j.ymeth.2021.09.010

Rahimi, K., Venø, M. T., Dupont, D. M. & Kjems, J. (2021). Nanopore sequencing of brain-derived full-length circRNAs reveals circRNA-specific exon usage, intron retention and microexons. Nature Communications, 12, Article 4825. https://doi.org/10.1038/s41467-021-24975-z

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Das Mahapatra, K., Pasquali, L., Søndergaard, J. N., Lapins, J., Nemeth, I. B., Baltás, E., Kemény, L., Homey, B., Moldovan, L. I., Kjems, J., Kutter, C., Sonkoly, E., Kristensen, L. S. & Pivarcsi, A. (2020). A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma. Scientific Reports, 10, Article 3637. https://doi.org/10.1038/s41598-020-59660-6

Venø, M. T., Reschke, C. R., Morris, G., Connolly, N. M. C., Su, J., Yan, Y., Engel, T., Jimenez-Mateos, E. M., Harder, L. M., Pultz, D., Haunsberger, S. J., Pal, A., Heller, J. P., Campbell, A., Langa, E., Brennan, G. P., Conboy, K., Richardson, A., Norwood, B. A. ... Henshall, D. C. (2020). A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. Proceedings of the National Academy of Sciences (PNAS), 117(27), 15977-15988. https://doi.org/10.1073/pnas.1919313117

Ramsay, E., Raviña, M., Sarkhel, S., Hehir, S., Cameron, N. R., Ilmarinen, T., Skottman, H., Kjems, J., Urtti, A., Ruponen, M. & Subrizi, A. (2020). Avoiding the pitfalls of siRNA delivery to the retinal pigment epithelium with physiologically relevant cell models. Pharmaceutics, 12(7), Article 667. https://doi.org/10.3390/pharmaceutics12070667

Yoshimoto, R., Rahimi, K., Hansen, T. B., Kjems, J. & Mayeda, A. (2020). Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats. iScience, 23(7), Article 101345. https://doi.org/10.1016/j.isci.2020.101345

Just, J., Yan, Y., Farup, J., Sieljacks, P., Sloth, M., Venø, M., Gu, T., de Paoli, F. V., Nyengaard, J. R., Bæk, R., Jørgensen, M. M., Kjems, J., Vissing, K. & Drasbek, K. R. (2020). Blood flow-restricted resistance exercise alters the surface profile, miRNA cargo and functional impact of circulating extracellular vesicles. Scientific Reports, 10(1), Article 5835. https://doi.org/10.1038/s41598-020-62456-3

Kirkegaard, K., Yan, Y., Sørensen, B. S., Hardason, T., Hanson, C., Ingerslev, H. J., Knudsen, U. B., Kjems, J., Lundin, K. & Ahlström, A. (2020). Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid. Journal of Assisted Reproduction and Genetics, 37(9), 2199–2209. https://doi.org/10.1007/s10815-020-01891-7

Hait, A. S., Olagnier, D., Sancho-Shimizu, V., Skipper, K. A., Helleberg, M., Larsen, S. M., Bodda, C., Moldovan, L. I., Ren, F., Brinck Andersen, N.-S., Thomsen, M. M., Freytag, M. R., Darmalinggam, S., Parkes, I., Kadekar, D. D., Rahbek, S. H., van der Horst, D., Kristensen, L. S., Eriksson, K. ... Mogensen, T. H. (2020). Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans. Science Immunology, 5(54), Article eabc2691. https://doi.org/10.1126/sciimmunol.abc2691

Omer, M., Andersen, V. L., Nielsen, J. S., Wengel, J. & Kjems, J. (2020). Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds. Molecular Therapy - Nucleic Acids, 22, 994-1003. https://doi.org/10.1016/j.omtn.2020.10.013

Mortensen, M. R., Skovsgaard, M. B., Märcher, A., Andersen, V. L., Palmfeldt, J., Nielsen, T. B., Tørring, T., Laursen, N. S., Andersen, K. R., Kjems, J. & Gothelf, K. V. (2020). Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling. Bioconjugate Chemistry, 31(5), 1295-1300. https://doi.org/10.1021/acs.bioconjchem.0c00151

Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J. ... LifeTime Community Working Groups (2020). LifeTime and improving European healthcare through cell-based interceptive medicine. Nature, 587, 377-386. https://doi.org/10.1038/s41586-020-2715-9

Lo, IJ., Hill, J., Vilhjálmsson, B. J. & Kjems, J. (2020). Linking the association between circRNAs and Alzheimer's disease progression by multi-tissue circular RNA characterization. RNA Biology, 17(12), 1789-1797. https://doi.org/10.1080/15476286.2020.1783487

Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020). Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin. Biomedicines, 8(11), 1-24. Article 450. https://doi.org/10.3390/biomedicines8110450

Yan, Y., Chang, C., Su, J., Venø, M. T. & Kjems, J. (2020). Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs). Biomedicines, 8(10), 1-17. Article 387. https://doi.org/10.3390/biomedicines8100387

Godskesen, L. E., Lassen, T. R., Jespersen, N. R., Siersbæk, M., Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G., Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J. (2020). Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial. Scientific Reports, 10(1), Article 9537. https://doi.org/10.1038/s41598-020-65692-9

Kristensen, L. S., Ebbesen, K. K., Sokol, M., Jakobsen, T., Korsgaard, U., Eriksen, A. C., Hansen, T. B., Kjems, J. & Hager, H. (2020). Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory. Nature Communications, 11, Article 4551. https://doi.org/10.1038/s41467-020-18355-2

Thomsen, R. P., Malle, M. G., Okholm, A. H., Krishnan, S., Bohr, S. S. R., Sørensen, R. S., Ries, O., Vogel, S., Simmel, F. C., Hatzakis, N. S. & Kjems, J. (2019). A large size-selective DNA nanopore with sensing applications. Nature Communications, 10(1), Article 5655. https://doi.org/10.1038/s41467-019-13284-1

Høiberg, H. C., Sparvath, S. M., Andersen, V. L., Kjems, J. & Andersen, E. S. (2019). An RNA origami octahedron with intrinsic siRNAs for potent gene knockdown. Biotechnology Journal, 14(1), Article 1700634. https://doi.org/10.1002/biot.201700634

Andersen, V. L., Vinther, M., Kumar, R., Ries, A., Wengel, J., Nielsen, J. S. & Kjems, J. (2019). A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics, 9(9), 2662-2677. https://doi.org/10.7150/thno.32060

Raniolo, S., Croce, S., Thomsen, R. P., Okholm, A. H., Unida, V., Iacovelli, F., Manetto, A., Kjems, J., Desideri, A. & Biocca, S. (2019). Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries. Nanoscale, 11(22), 10808-10818. https://doi.org/10.1039/c9nr02006c

Costard, L. S., Neubert, V., Venø, M. T., Su, J., Kjems, J., Connolly, N. M. C., Prehn, J. H. M., Schratt, G., Henshall, D. C., Rosenow, F. & Bauer, S. (2019). Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression. Brain Stimulation, 12(6), 1390-1401. https://doi.org/10.1016/j.brs.2019.06.009

Klein, W. P., Thomsen, R. P., Turner, K. B., Walper, S. A., Vranish, J., Kjems, J., Ancona, M. G. & Medintz, I. L. (2019). Enhanced Catalysis from Multienzyme Cascades Assembled on a DNA Origami Triangle. ACS Nano, 13(12), 13677-13689. https://doi.org/10.1021/acsnano.9b05746

Krissanaprasit, A., Key, C., Fergione, M., Froehlich, K., Pontula, S., Hart, M., Carriel, P., Kjems, J., Andersen, E. S. & LaBean, T. H. (2019). Genetically Encoded, Functional Single-Strand RNA Origami: Anticoagulant. Advanced Materials, 31(21), Article 1808262. https://doi.org/10.1002/adma.201808262

Moldovan, L.-I., Hansen, T. B., Venø, M. T., Okholm, T. L. H., Andersen, T. L., Hager, H., Iversen, L., Kjems, J., Johansen, C. & Kristensen, L. S. (2019). High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome. BMC Medical Genomics, 12(1), Article 174. https://doi.org/10.1186/s12920-019-0616-2

Vu-Quang, H., Vinding, M. S., Jakobsen, M., Song, P., Dagnaes-Hansen, F., Nielsen, N. C. & Kjems, J. (2019). Imaging rheumatoid arthritis in mice using combined near infrared and ¹⁹F magnetic resonance modalities. Scientific Reports, 9, Article 14314. https://doi.org/10.1038/s41598-019-50043-0

Yan, Y., Chang, C. C., Venø, M. T., Mothershead, C. R., Su, J. & Kjems, J. (2019). Isolating, Sequencing and Analyzing Extracellular MicroRNAs from Human Mesenchymal Stem Cells. Journal of visualized experiments : JoVE, 2019(145), Article e58655. https://doi.org/10.3791/58655

Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019). Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. Molecular Therapy, 27(8), 1424-1435. https://doi.org/10.1016/j.ymthe.2019.05.002

Nielsen, T. B., Thomsen, R. P., Mortensen, M. R., Kjems, J., Nielsen, P. F., Nielsen, T. E., Kodal, A. L. B., Cló, E. & Gothelf, K. V. (2019). Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM. Angewandte Chemie International Edition, 58(27), 9068-9072. https://doi.org/10.1002/anie.201903134

Vu-Quang, H., Vinding, M. S., Nielsen, T., Ullisch, M. G., Nielsen, N. C., Nguyen, D. T. & Kjems, J. (2019). Pluronic F127-folate coated super paramagenic iron oxide nanoparticles as contrast agent for cancer diagnosis in magnetic resonance imaging. Polymers, 11(4), Article 743. https://doi.org/10.3390/polym11040743

Liu, T., Song, P., Märcher, A., Kjems, J., Yang, C. & Gothelf, K. V. (2019). Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab‐DNA conjugates. ChemBioChem, 20(8), 1014-1018. https://doi.org/10.1002/cbic.201800685

Jepsen, M. D. E., Sørensen, R. S., Maffeo, C., Aksimentiev, A., Kjems, J. & Birkedal, V. (2019). Single molecule analysis of structural fluctuations in DNA nanostructures. Nanoscale, 11(39), 18475-18482. https://doi.org/10.1039/c9nr03826d

Verboom, K., Everaert, C., Bolduc, N., Livak, K. J., Yigit, N., Rombaut, D., Anckaert, J., Lee, S., Venø, M. T., Kjems, J., Speleman, F., Mestdagh, P. & Vandesompele, J. (2019). SMARTer single cell total RNA sequencing. Nucleic Acids Research, 47(16), Article e93. https://doi.org/10.1093/nar/gkz535

Prabha, R. D., Nair, B. P., Ditzel, N., Kjems, J., Nair, P. D. & Kassem, M. (2019). Strontium functionalized scaffold for bone tissue engineering. Materials Science and Engineering C: Biomimetic Materials, Sensors and Systems, 94, 509-515. https://doi.org/10.1016/j.msec.2018.09.054

Kristensen, L. S., Schertz Andersen, M., Stagsted, L. V. W., Ebbesen, K., Hansen, T. B. & Kjems, J. (2019). The biogenesis, biology and characterization of circular RNAs. Nature Reviews. Genetics, 20(11), 675-691. https://doi.org/10.1038/s41576-019-0158-7

Knudsen, C. H., ásgrímsdóttir, E. S., Rahimi, K., Gill, K. P., Frandsen, S., Buchholdt, S. H., Chen, M., Kjems, J., Febbraro, F. & Denham, M. (2018). A modified monomeric red fluorescent protein reporter for assessing CRISPR activity. Frontiers in Cell and Developmental Biology, 6(MAY), Article 54. https://doi.org/10.3389/fcell.2018.00054

Nielsen, C. K., Subbiahdoss, G., Zeng, G., Salmi, Z., Kjems, J., Mygind, T., Snabe, T. & Meyer, R. L. (2018). Antibacterial isoeugenol coating on stainless steel and polyethylene surfaces prevents biofilm growth. Journal of Applied Microbiology, 124(1), 179-187. https://doi.org/10.1111/jam.13634