DNA Origami Design Software

The software package distributes a sequence editor with a set of tools for designing DNA origami structures:

• Bitmap reader - import any shape as design object.
• DNA origami fold - automatically finds a folding path through a shape.
• 3D generator - automatically generates a 3D atomic model of your design.
• Oligotrack - accepts any sequence to be integrated in your design and outputs an oligo list for ordering.

Download:

• The program currently runs on Mac and Linux
• The program might be ported for Windows some time in the future, but for the moment here is a protocol on how to run SARSE in Virtualbox on Windows.
• Click here to download SARSE - DNA origami v1.1
• P.S. The earlier download file was dysfunctional.

Get started:

• How to design a dolphin shape in DNA
• Nature Network protocol about DNA box design
• See SARSE wiki for documentation and tutorials.

For usage please cite:

• Andersen et al. DNA Origami Design of Dolphin-Shaped Structures with Flexible Tails. ACS nano (2008)

Contact:

Please send an email to Ebbe S. Andersen marked "SARSE mailinglist" if you want to stay informed about updates of the SARSE - DNA origami package or marked "SARSE comment" if you have any questions or suggestions.

Related software:

• caDNAno
• GIDEON
• NanoEngineer-1
• UNIQUiMER 3D