Petersen, S, Kläning, E, Andersen, B, Cameron, J
, Sørensen, ES & Howard, K 2016, '
Neonatal Fc Receptor Binding Tolerance toward the Covalent Conjugation of Payloads to Cysteine 34 of Human Albumin Variants',
Molecular Pharmaceutics, vol. 13, no. 2, pp. 677–682.
https://doi.org/10.1021/acs.molpharmaceut.5b00605
Whitehead, BJ, Wu, L
, Hvam, ML, Aslan, H, Dong, M, Dyrskjøt, L, Ostenfeld, MS, Moein Moghimi, S
& Howard, K 2015, '
Tumour exosomes display different differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness',
Journal of Extracellular Vesicles, vol. 4, 29685.
https://doi.org/10.3402/jev.v4.29685
Ebbesen, MF, Olesen, MTJ, Gjelstrup, MC, Pakula, MM, Larsen, EK, Hansen, IM, Hansen, PL, Mollenhauer, J, Malle, BM
& Howard, K 2015, '
Tunable CD44-Specific Cellular Retargeting with Hyaluronic Acid Nanoshells',
Pharmaceutical Research, vol. 32, no. 4, pp. 1462-1474.
https://doi.org/10.1007/s11095-014-1552-7
Yang, HY, Vonk, LA, Licht, R, Van Boxtel, AMG, Bekkers, JEJ, Kragten, AHM
, Hein, S, Varghese, OP
, Howard, K, Cumhur Öner, F, Dhert, WJA & Creemers, LB 2014, '
Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells',
European Journal of Pharmaceutical Sciences, vol. 53, no. 1, pp. 35-44.
https://doi.org/10.1016/j.ejps.2013.12.006Jeppesen, DK, Hvam, ML, Primdahl-Bengtson, B
, Boysen, AT, Whitehead, B, Dyrskjøt, L, Orntoft, TF, Howard, K & Ostenfeld, MS 2014, '
Comparative analysis of discrete exosome fractions obtained by differential centrifugation',
Journal of Extracellular Vesicles, vol. 3, 25011, pp. 1-16.
https://doi.org/10.3402/jev.v3.25011
Ebbesen, M, Bienk, K, Deleuran, BW & Howard, K 2014, '
Extended blood circulation and accumulation of a p(HPMA-co-AzMA)-based nanoconjugate in a murine model of rheumatoid arthritis',
Molecular and Cellular Therapies, vol. 2, no. 29.
https://doi.org/10.1186/2052-8426-2-29
Ebbesen, MF, Bienk, K, Deleuran, BW & Howard, K 2014, '
Extended circulation and accumulation of p(HPMA-co-AzMA) and accumulation in arthritic joints', 41st Annual Meeting & Exposition of the Controlled Release Society, July 13-16, 2014 Chicago, USA , Chicago, United States,
13/07/2014 -
16/07/2014.
Rubert, M, Fang-Li, Y
, Aslan, H, Yu, Y
, Howard, KA, Dong, MD, Besenbacher, F & Chen, M 2014, '
Inflammatory response of RAW 264.7 cells to ultraporous interweaving PCL-PEO electrospun microfibers',
Journal of Tissue Engineering and Regenerative Medicine, vol. 8, pp. 249-249.
Jeppesen, DK, Nawrocki, A
, Jensen, SG, Thorsen, K, Whitehead, B, Howard, K, Andersen, LD, Orntoft, TF, Larsen, MR
& Ostenfeld, MS 2014, '
Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors',
Proteomics, vol. 14, no. 6, pp. 699-712.
https://doi.org/10.1002/pmic.201300452
Miclaus, T, Bochenkov, V, Ogaki, R, Howard, K & Sutherland, DS 2014, '
Spatial Mapping and Quantification of Soft and Hard Protein Coronas at Silver Nanocubes',
Nano Letters, vol. 14, no. 4, pp. 2086-2093.
https://doi.org/10.1021/nl500277c
Whitehead, BJ, Hvam, ML, Bienk, K, Ostenfeld, MS & Howard, K 2014, '
The Application of a Fluorescent Pre-Labelling Method for Evaluation of Exosome Biodistribution', The 41st Annual Meeting & Exposition of the Controlled Release Society, Chicago, United States,
13/07/2014 -
16/07/2014.
Li, YY, Femenias, MR, Aslan, HH, Yu, YY
, Howard, K, Dong, MD, Besenbacher, FF & Chen, MM 2014, '
Ultraporous interweaving electrospun microfibers from PCL-PEO binary blends and their inflammatory responses',
Nanoscale, vol. 6, no. 6, pp. 3392-3402.
https://doi.org/10.1039/c3nr06197c
Ostenfeld, MS, Jeppesen, DK, Laurberg, JR, Boysen, A, Howard, K, Christensen, EI, Morth, P, Bui, KH, Theodorescu, D
, Jensen, JB, Borre, M, Dyrskjøt, L & Ørntoft, TF 2013, '
Keystone Symposia "ncRNAs in Development and Cancer", Vancouver, Canada: Increased release of exosomes and export of invasion-modulating miRNAs miR921, -23b, -and -224 from metastatic urothelial carcinoma cells'.
Gonzalez, BB, Nielsen, EJB, Thomsen, TB & Howard, K 2013,
Mucosal Delivery of RNAi Therapeutics. in KA Howard (ed.),
RNA Interference from Biology to Therapeutics. Springer, Advances in Delivery Science and Technology, pp. 97-125. <
http://link.springer.com/chapter/10.1007%2F978-1-4614-4744-3_5#page-1>
Nawroth, I, Alsner, J, Deleuran, BW, Dagnæs-Hansen, F, Yang, C, Horsman, MR, Overgaard, J, Howard, K, Kjems, J & Gao, S 2013, '
Peritoneal macrophages mediated delivery of chitosan/siRNA nanoparticle to the lesion site in a murine radiation-induced fibrosis model',
Acta Oncologica, vol. 52, no. 8, pp. 1730-1738.
https://doi.org/10.3109/0284186X.2012.726373
Gonzalez, BB, Dagnæs-Hansen, F, Fenton, RA, Gao, S, Hein, S, Dong, M, Kjems, J & Howard, KA 2013, '
Protection and systemic translocation of siRNA following oral administration of chitosan/siRNA nanoparticles',
Molecular Therapy - Nucleic Acids, vol. 2, no. 1, e76, pp. 1-8.
https://doi.org/10.1038/mtna.2013.2
Ebbesen, MF, Whitehead, BJ, Gonzalez, BB, Kingshott, P
& Howard, K 2013, '
Surface analysis of PEGylated nano-shields on nanoparticles installed by hydrophobic anchors',
Pharmaceutical Research, vol. 30, no. 7, pp. 1758-1767.
https://doi.org/10.1007/s11095-013-1018-3
Ebbesen, MF, Schaffert, DH, Crowley, ML, Oupický, D
& Howard, K 2013, '
Synthesis of click-reactive HPMA copolymers using RAFT polymerization for drug delivery applications',
Journal of Polymer Science. Part A, Polymer Chemistry, vol. 51, no. 23, pp. 5091-5099.
https://doi.org/10.1002/pola.26941
Larsen, EKU, Nielsen, T, Wittenborn, T, Rydtoft, LM, Lokanathan, AR, Hansen, L, Østergaard, L, Kingshott, P, Howard, KA, Besenbacher, F, Nielsen, NC & Kjems, J 2012, '
Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors',
Nanoscale, vol. 4, no. 7, pp. 2352-2361 .
https://doi.org/10.1039/C2NR11554A
Chen, M, Gao, S, Dong, M, Song, J, Yang, C, Howard, KA, Kjems, J & Besenbacher, F 2012, '
Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery',
A C S Nano, vol. 6, no. 6, pp. 4835-4844.
https://doi.org/10.1021/nn300106t
de Paz, L
, Resin, A, Howard, K, Sutherland, DS & Wejse, P 2011, '
Antimicrobial effect of chitosan nanoparticles on streptococcus mutans biofilms',
Applied and Environmental Microbiology, vol. 77, no. 11, pp. 3892-3895.
Rahbek, UL, Nielsen, AF, Dong, M, You, Y, Chauchereau, A, Oupicky, D
, Besenbacher, F, Kjems, J & Howard, KA 2010, '
Bioresponsive hyperbranched polymers for siRNA and miRNA delivery',
Journal of Drug Targeting, vol. 18, no. 10, pp. 812-20.
https://doi.org/10.3109/1061186X.2010.527982
Mittnacht, U, Hartmann, H
, Hein, S, Oliveira, H
, Dong, M, Pêgo, AP
, Kjems, J, Howard, KA & Schlosshauer, B 2010, '
Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth',
Nano Letters, vol. 10, no. 10, pp. 3933-9.
https://doi.org/10.1021/nl1016909Nawroth, I, Alsner, J, Behlke, MA
, Besenbacher, F, Overgaard, J, Howard, KA & Kjems, J 2010, '
Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFα prevents radiation-induced fibrosis',
Radiotherapy & Oncology, vol. 97, no. 1, pp. 143-8.
https://doi.org/10.1016/j.radonc.2010.09.010
Nielsen, EJB, Nielsen, JM, Becker, D, Karlas, A, Prakash, H
, Glud, SZ, Merrison, J, Besenbacher, F, Meyer, TF
, Kjems, J & Howard, KA 2010, '
Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles',
Pharmaceutical Research, vol. 27, no. 12, pp. 2520-7.
https://doi.org/10.1007/s11095-010-0255-y
Andersen, MØ, Nygaard, JV, Burns, JS
, Raarup, MK, Nyengaard, JR, Bünger, C, Besenbacher, F, Howard, KA, Kassem, M & Kjems, J 2010, '
siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells',
Molecular Therapy, vol. 18, no. 11, pp. 2018-2027.
https://doi.org/10.1038/mt.2010.166
Kjems, J, Overgaard, J, Howard, K, Alsner, J, Besenbacher, F & Nawroth, I,
Treatment of radiation-induced fibrosis, Patent No. WO2010085959A1.
Hartmann, H, Lakner, U
, Andersen, MØ, Kjems, J, Howard, KA & Schloßhauer, B 2009, '
Carrier Matrix for siRNA-Mediated Gene Knock Down to Promote Neuronal Regeneration.',
Tissue Engineering. Part A. Tissue Engineering, no. 3, pp. 718.
Mistry, A
, Glud, SZ, Kjems, J, Nyengaard, JR, Howard, KA, Stolnik, S & Illum, L 2009, '
Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium',
Journal of Drug Evaluation, vol. 17, no. 7, pp. 543-552.
https://doi.org/10.1080/10611860903055470Glud, SZ, Bramsen, JB, Dagnaes-Hansen, F, Wengel, J
, Howard, KA, Nyengaard, JR & Kjems, J 2009, '
Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration',
Oligonucleotides, vol. 19, no. 2, pp. 163-8.
https://doi.org/10.1089/oli.2008.0175
Larsen, EKU, Nielsen, T, Wittenborn, T, Birkedal, H, Vorup-Jensen, T, Jakobsen, MH
, Østergaard, L, Horsman, MR, Besenbacher, F, Howard, KA & Kjems, J 2009, '
Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors',
A C S Nano, vol. 3, no. 7, pp. 1947-51.
https://doi.org/10.1021/nn900330m
Gao, S, Dagnæs-Hansen, F, Nielsen, EJB, Wengel, J
, Besenbacher, F, Howard, KA & Kjems, J 2009, '
The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice',
Molecular Therapy, vol. 17, no. 7, pp. 1225-1233.
https://doi.org/10.1038/mt.2009.91
Howard, KA, Paludan, SR, Behlke, MA
, Besenbacher, F, Deleuran, BW & Kjems, J 2008, '
Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model',
Molecular Therapy, vol. 17, no. 1, pp. 162-168.
https://doi.org/10.1038/mt.2008.220
Andersen, MØ, Howard, KA, Paludan, SR, Besenbacher, F & Kjems, J 2008, '
Delivery of siRNA from lyophilized polymeric surfaces',
Biomaterials, vol. 29, no. 4, pp. 506-512.
https://doi.org/10.1016/j.biomaterials.2007.10.003
Rahbek, UL, Howard, KA, Oupicky, D, Manickam, DS
, Dong, M, Nielsen, AF, Hansen, TB, Besenbacher, F & Kjems, J 2008, '
Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides',
Journal of Gene Medicine, vol. 10, no. 1, pp. 81-93.
https://doi.org/10.1002/jgm.1120
Nygaard, JV, Andersen, MØ, Howard, KA, Foss, M, Bünger, C, Kjems, J & Besenbacher, F 2008, '
Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy',
Biotechnology and Bioengineering (Print), vol. 100, no. 4, pp. 820-9.
https://doi.org/10.1002/bit.21796
Xu, S, Dong, M, Liu, X, Howard, KA, Kjems, J & Besenbacher, F 2007, '
Direct force measurements between siRNA and chitosan molecules using force spectroscopy',
Biophysical Journal, vol. 93, no. 3, pp. 952-9.
https://doi.org/10.1529/biophysj.106.093229
Bak, RO, Andersen, MØ, Howard, KA & Kjems, J 2007, '
Localized Delivery of Lyophilized siRNA polyplexes', INASCON, Aarhus, Denmark,
07/07/2007 -
07/10/2007.
