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Interdisciplinary Nanoscience Center

Publications from Nanomedicine

Publications

Jakobsen, M. R., Haasnoot, J., Wengel, J., Berkhout, B. & Kjems, J. (2007). Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites. Retrovirology, 4(29), 1-13. https://doi.org/10.1186/1742-4690-4-29

Lykke-Andersen, S., Piñol-Roma, S. & Kjems, J. (2007). Alternative splicing of the ADAR1 transcript in a region that functions either as a 5'-UTR or an ORF. RNA, 13(10), 1732-1744. https://doi.org/10.1261/rna.567807

Bramsen, J. B., Laursen, M. B., Damgaard, C. K., Lena, S. W., Babu, B. R., Wengel, J. & Kjems, J. (2007). Improved silencing properties using small internally segmented interfering RNAs. Nucleic Acids Research, 35(17), 5886-5897. https://doi.org/10.1093/nar/gkm548

Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNA interference therapeutics. Expert opinion on biological therapy, 7(12), 1811-1822. https://doi.org/10.1517/14712598.7.12.1811

Odadzic, D., Bramsen, J. B., Smicius, R., Bus, C., Kjems, J. & Engels, J. W. (2008). Synthesis of 2'-O-modified adenosine building blocks and application for RNA interference. Bioorganic & Medicinal Chemistry, 16(1), 518-529. https://doi.org/10.1016/j.bmc.2007.09.019

Andersen, M. Ø., Howard, K. A., Paludan, S. R., Besenbacher, F. & Kjems, J. (2008). Delivery of siRNA from lyophilized polymeric surfaces. Biomaterials, 29(4), 506-512. https://doi.org/10.1016/j.biomaterials.2007.10.003

Torarinsson, E., Yao, Z., Wiklund, E. D., Bramsen, J. B., Hansen, C. A., Kjems, J., Tommerup, N., Ruzzo, W. L. & Gorodkin, J. (2008). Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions. Genome Research, 18(2), 242-251. https://doi.org/10.1101/gr.6887408

Astakhova, I., Korshun, V. A., Jahn, K., Kjems, J. & Wengel, J. (2008). Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture. Bioconjugate Chemistry, 19(10), 1995-2007. https://doi.org/10.1021/bc800202v

Otero Martin, R., Xu, W., Lukas, M., Kelly, R. E. A., Laegsgaard, E., Stensgaard, I., Kjems, J., Kantorovich, L. N. & Besenbacher, F. (2008). Specificity of Watson-Crick Base Pairing on a Solid Surface Studied at the Atomic Scale. Angewandte Chemie, 47(50), 9673-9676. https://doi.org/10.1002/anie.200803333

Howard, K. A., Paludan, S. R., Behlke, M. A., Besenbacher, F., Deleuran, B. W. & Kjems, J. (2008). Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Molecular Therapy, 17(1), 162-168. https://doi.org/10.1038/mt.2008.220

Bramsen, J. B., Laursen, M. B., Nielsen, A. F., Hansen, T. B., Bus, C., Langkjær, N., Babu, B. R., Højland, T., Abramov, M., Van Aerschot, A., Odadzic, D., Smicius, R., Haas, J., Andree, C., Barman, J., Wenska, M., Srivastava, P., Zhou, C., Honcharenko, D. ... Kjems, J. (2009). A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity. Nucleic Acids Research, 37(9), 2867-81. https://doi.org/10.1093/nar/gkp106

Schyth, B. D., Bramsen, J. B., Pakula, M. M., Larashati, S., Kjems, J., Wengel, J. & Lorenzen, N. (2012). In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important. Nucleic Acids Research, 40(10), 4653-4665. https://doi.org/10.1093/nar/gks033

Bellemer, C., Bortolin-Cavaillé, M.-L., Schmidt, U., Jensen, S. M. R., Kjems, J., Bertrand, E. & Cavaillé, J. (2012). Microprocessor dynamics and interactions at endogenous imprinted C19MC microRNA genes. Journal of Cell Science, 125, 2709-2720 . https://doi.org/10.1242/jcs.100354

Novotny, G. W., Belling, K. C., Bramsen, J. B., Nielsen, J. E., Bork-Jensen, J., Almstrup, K., Sonne, S. B., Kjems, J., Rajpert-De Meyts, E. & Leffers, H. (2012). MicroRNA expression profiling of carcinoma in situ (CIS) cells of the testis. Endocrine - Related Cancer, 365-379. https://doi.org/10.1530/ERC-11-0271

Larsen, E. K. U., Nielsen, T., Wittenborn, T., Rydtoft, L. M., Lokanathan, A. R., Hansen, L., Østergaard, L., Kingshott, P., Howard, K. A., Besenbacher, F., Nielsen, N. C. & Kjems, J. (2012). Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. Nanoscale, 4(7), 2352-2361 . https://doi.org/10.1039/C2NR11554A

Mistry, A., Glud, S. Z., Kjems, J., Nyengaard, J. R., Howard, K. A., Stolnik, S. & Illum, L. (2009). Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium. Journal of Drug Evaluation, 17(7), 543-552. https://doi.org/10.1080/10611860903055470

Pedersen, M. B., Zhou, X., Larsen, E. K. U., Sørensen, U. S., Kjems, J., Nygaard, J. V., Nyengaard, J. R., Meyer, R. L., Boesen, T. & Vorup-Jensen, T. (2010). Curvature of Synthetic and Natural Surfaces is an Important Target Feature in Classical Pathway Complement Activation. Journal of Immunology, 184(4), 1931-1945. https://doi.org/10.4049/jimmunol.0902214

Birkedal, V., Dong, M., Golas, M. M., Sander, B., Andersen, E. S., Gothelf, K. V., Besenbacher, F. & Kjems, J. (2011). Single molecule microscopy methods for the study of DNA origami structures. Microscopy Research and Technique, 74(7), 688-698. https://doi.org/10.1002/jemt.20962

Zhang, Z., Olsen, E. M., Kryger, M., Voigt, N. V., Tørring, T., Gültekin, E., Nielsen, M., MohammadZadegan, R., Andersen, E. S., Nielsen, M. M., Kjems, J., Birkedal, V. & Gothelf, K. V. (2011). A DNA tile actuator with eleven discrete states. Angewandte Chemie International Edition, 50(17), 3983-7. https://doi.org/10.1002/anie.201007642

Jepsen, M. B., Beerens, N., Nechyponuk-Zloy, V., Besenbacher, F., Kjems, J. & Birkedal, V. (2011). Single molecule FRET microscopy studies of tRNA annealing onto the HIV-1 genome. Poster session presented at International Bunsen Discussion Meeting Förster resonance energy transfer in life science, Germany.

Revised 29.01.2025

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Anne Færch Nielsen