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Two Receptor Binding Strategy of SARS-CoV-2 Is Mediated by Both the N-Terminal and Receptor-Binding Spike Domain.
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4-Oxo-2-nonenal-Induced α-Synuclein Oligomers Interact with Membranes in the Cell, Leading to Mitochondrial Fragmentation.
Biochemistry,
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Alzheimer's Progenitor Amyloid-β Targets and Dissolves Microbial Amyloids and Impairs Biofilm Function.
Advanced Science,
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Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions.
Chemical Science,
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Elevated concentrations cause upright alpha-synuclein conformation at lipid interfaces.
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FapA is an Intrinsically Disordered Chaperone for Pseudomonas Functional Amyloid FapC.
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GFP fusions of Sec-routed extracellular proteins in Staphylococcus aureusreveal surface-associated coagulase in biofilms.
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Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation.
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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease.
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Periostin C-Terminal Is Intrinsically Disordered and Interacts with 143 Proteins in an In Vitro Epidermal Model of Atopic Dermatitis.
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Sequence-targeted Peptides Divert Functional Bacterial Amyloid Towards Destabilized Aggregates and Reduce Biofilm Formation.
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Tau Fibrillation Induced by Heparin or a Lysophospholipid Show Different Initial Oligomer Formation.
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The anti-platelet drug ticlopidine inhibits FapC fibrillation and biofilm production: Highlighting its antibiotic activity.
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The impact of α-synuclein aggregates on blood-brain barrier integrity in the presence of neurovascular unit cells.
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Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells.
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A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers.
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A Semester-Long Learning Path Teaching Computational Skills via Molecular Graphics in PyMOL.
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Bidirectional protein-protein interactions control liquid-liquid phase separation of PSD-95 and its interaction partners.
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Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation.
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Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization.
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Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response.
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The changing face of SDS denaturation: Complexes of Thermomyces lanuginosus lipase with SDS at pH 4.0, 6.0 and 8.0.
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The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
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Uncovering the universality of self-replication in protein aggregation and its link to disease.
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A semi high-throughput method for real-time monitoring of curli producing Salmonella biofilms on air-solid interfaces.
Biofilm,
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Breakdown of supersaturation barrier links protein folding to amyloid formation.
Communications Biology,
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C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition.
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Cys-labelling kinetics of membrane protein GlpG: a role for specific SDS binding and micelle changes? Biophysical Journal,
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