Yoshimoto, R.
, Rahimi, K., Hansen, T. B., Kjems, J. & Mayeda, A. (2020).
Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats.
iScience,
23(7), Article 101345.
https://doi.org/10.1016/j.isci.2020.101345
Yan, Y., Chang, C., Su, J., Venø, M. T. & Kjems, J. (2020).
Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs).
Biomedicines,
8(10), 1-17. Article 387.
https://doi.org/10.3390/biomedicines8100387
Venø, M. T., Reschke, C. R., Morris, G., Connolly, N. M. C.
, Su, J., Yan, Y., Engel, T., Jimenez-Mateos, E. M., Harder, L. M., Pultz, D., Haunsberger, S. J., Pal, A., Heller, J. P., Campbell, A., Langa, E., Brennan, G. P., Conboy, K., Richardson, A., Norwood, B. A. ... Henshall, D. C. (2020).
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy.
Proceedings of the National Academy of Sciences,
117(27), 15977-15988.
https://doi.org/10.1073/pnas.1919313117
Stoll, L., Rodríguez-Trejo, A., Guay, C., Brozzi, F., Bayazit, M. B., Gattesco, S., Menoud, V., Sobel, J., Marques, A. C.
, Venø, M. T., Esguerra, J. L. S., Barghouth, M., Suleiman, M., Marselli, L.
, Kjems, J., Eliasson, L., Renström, E., Bouzakri, K., Pinget, M. ... Regazzi, R. (2020).
A circular RNA generated from an intron of the insulin gene controls insulin secretion.
Nature Communications,
11, Article 5611.
https://doi.org/10.1038/s41467-020-19381-w
Ramsay, E., Raviña, M., Sarkhel, S., Hehir, S., Cameron, N. R., Ilmarinen, T., Skottman, H.
, Kjems, J., Urtti, A., Ruponen, M.
& Subrizi, A. (2020).
Avoiding the pitfalls of siRNA delivery to the retinal pigment epithelium with physiologically relevant cell models.
Pharmaceutics,
12(7), Article 667.
https://doi.org/10.3390/pharmaceutics12070667
Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N.
, Kjems, J. ... LifeTime Community Working Groups (2020).
LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature,
587, 377-386.
https://doi.org/10.1038/s41586-020-2715-9
Omer, M., Andersen, V. L., Nielsen, J. S., Wengel, J.
& Kjems, J. (2020).
Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds.
Molecular Therapy - Nucleic Acids,
22, 994-1003.
https://doi.org/10.1016/j.omtn.2020.10.013
Mortensen, M. R., Skovsgaard, M. B., Märcher, A., Andersen, V. L., Palmfeldt, J., Nielsen, T. B., Tørring, T., Laursen, N. S., Andersen, K. R., Kjems, J. & Gothelf, K. V. (2020).
Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling.
Bioconjugate Chemistry,
31(5), 1295-1300.
https://doi.org/10.1021/acs.bioconjchem.0c00151
Kristensen, L. S., Ebbesen, K. K., Sokol, M., Jakobsen, T., Korsgaard, U., Eriksen, A. C.
, Hansen, T. B., Kjems, J. & Hager, H. (2020).
Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory.
Nature Communications,
11, Article 4551.
https://doi.org/10.1038/s41467-020-18355-2
Kirkegaard, K., Yan, Y., Sørensen, B. S., Hardason, T., Hanson, C., Ingerslev, H. J.
, Knudsen, U. B., Kjems, J., Lundin, K. & Ahlström, A. (2020).
Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid.
Journal of Assisted Reproduction and Genetics,
37(9), 2199–2209.
https://doi.org/10.1007/s10815-020-01891-7
Just, J., Yan, Y., Farup, J., Sieljacks, P., Sloth, M., Venø, M., Gu, T., de Paoli, F. V., Nyengaard, J. R., Bæk, R., Jørgensen, M. M.
, Kjems, J., Vissing, K. & Drasbek, K. R. (2020).
Blood flow-restricted resistance exercise alters the surface profile, miRNA cargo and functional impact of circulating extracellular vesicles.
Scientific Reports,
10(1), Article 5835.
https://doi.org/10.1038/s41598-020-62456-3
Hait, A. S., Olagnier, D., Sancho-Shimizu, V.
, Skipper, K. A., Helleberg, M.
, Larsen, S. M., Bodda, C., Moldovan, L. I., Ren, F., Brinck Andersen, N-S., Thomsen, M. M., Freytag, M. R., Darmalinggam, S., Parkes, I.
, Kadekar, D. D., Rahbek, S. H., van der Horst, D., Kristensen, L. S., Eriksson, K.
... Mogensen, T. H. (2020).
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans.
Science Immunology,
5(54), Article eabc2691.
https://doi.org/10.1126/sciimmunol.abc2691
Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020).
Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.
Biomedicines,
8(11), 1-24. Article 450.
https://doi.org/10.3390/biomedicines8110450
Godskesen, L. E.
, Lassen, T. R., Jespersen, N. R., Siersbæk, M.
, Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G.
, Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J. (2020).
Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial.
Scientific Reports,
10(1), Article 9537.
https://doi.org/10.1038/s41598-020-65692-9
Das Mahapatra, K., Pasquali, L., Søndergaard, J. N., Lapins, J., Nemeth, I. B., Baltás, E., Kemény, L., Homey, B.
, Moldovan, L. I., Kjems, J., Kutter, C., Sonkoly, E.
, Kristensen, L. S. & Pivarcsi, A. (2020).
A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.
Scientific Reports,
10, Article 3637.
https://doi.org/10.1038/s41598-020-59660-6
Meyer, R. L., Walther, R., Nielsen, S. M., Andersen, P. O., Hansen, L., Vu-Quang, H., Kjems, J. & Zelikin, A. N. (2019).
Delivering antibiotics locally to biofilms by targeted drug delivery and prodrug therapy. Abstract from Eurobiofilms 2019, Glasgow, United Kingdom.
Kristensen, L. S., Schertz Andersen, M., Stagsted, L. V. W., Ebbesen, K., Hansen, T. B. & Kjems, J. (2019).
The biogenesis, biology and characterization of circular RNAs.
Nature Reviews. Genetics,
20(11), 675-691.
https://doi.org/10.1038/s41576-019-0158-7
Yan, Y., Chang, C. C., Venø, M. T., Mothershead, C. R., Su, J. & Kjems, J. (2019).
Isolating, Sequencing and Analyzing Extracellular MicroRNAs from Human Mesenchymal Stem Cells.
Journal of visualized experiments : JoVE,
2019(145), Article e58655.
https://doi.org/10.3791/58655
Vu-Quang, H., Vinding, M. S., Jakobsen, M., Song, P., Dagnaes-Hansen, F., Nielsen, N. C. & Kjems, J. (2019).
Imaging rheumatoid arthritis in mice using combined near infrared and 19F magnetic resonance modalities.
Scientific Reports,
9, Article 14314.
https://doi.org/10.1038/s41598-019-50043-0