Andreasen, M., Nielsen, S. B., Runager, K., Christiansen, G.
, Nielsen, N. C., Enghild, J. J. & Otzen, D. (2012).
Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways with Different Oligomeric Intermediates.
Journal of Biological Chemistry,
287(41), 34730-34742.
https://doi.org/10.1074/jbc.M112.379552
Pedersen, L. R. L., Nielsen, S. B., Hansted, J. G., Petersen, T. E.
, Otzen, D. E. & Sørensen, E. S. (2012).
PP3 forms stable tetrameric structures through hydrophobic interactions via the C-terminal amphipathic helix and undergoes reversible thermal dissociation and denaturation.
F E B S Journal,
279(2), 336-47.
https://doi.org/10.1111/j.1742-4658.2011.08428.x
Pedersen, L. R. L., Hansted, J. G., Nielsen, S. B., Petersen, T. E., Sørensen, U. S.
, Otzen, D. & Sørensen, E. S. (2012).
Proteolytic activation of proteose peptone component 3 by release of a C-terminal peptide with antibacterial properties.
Journal of Dairy Science,
95(6), 2819-2829.
https://doi.org/10.3168/jds.2011-4837
Lorenzen, N., Cohen, S. I. A., Nielsen, S. B., Herling, T. W., Christiansen, G., Dobson, C. M., T. P. Knowles, T.
& Otzen, D. (2012).
Role of elongation and secondary pathways in S6 amyloid fibril growth.
Biophysical Journal,
102(9), 2167-2175.
https://doi.org/10.1016/j.bpj.2012.03.047
Kalashnyk, N., Nielsen, J. T., Nielsen, E. H.
, Skrydstrup, T., Otzen, D., Lægsgaard, E., Wang, C.
, Besenbacher, F., Nielsen, N. C. & Linderoth, T. R. (2012).
Scanning tunneling microscopy reveals single-molecule insights into the self-assembly of amyloid fibrils.
A C S Nano,
6(8), 6882-6889.
https://doi.org/10.1021/nn301708d
Du, X., Wang, L., Wang, Y.
, Andreasen, M., Zhan, D., Feng, Y., Li, M., Zhao, M.
, Otzen, D., Xue, D., Yang, Y. & Liu, R. (2011).
Aβ1-16 Can Aggregate and induce the Production of Reactive Oxygen Species, Nitric Oxide, and Inflammatory Cytokines.
Journal of Alzheimer's Disease,
27(2), 401-413.
https://doi.org/10.3233/JAD-2011-110476
Dueholm, M. S., Nielsen, S. B., Hein, K. L.
, Nissen, P., Chapman, M., Christiansen, G., Nielsen, P. H.
& Otzen, D. E. (2011).
Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation.
Biochemistry,
50(39), 8281-90.
https://doi.org/10.1021/bi200967c
Runager, K.
, Basaiawmoit, R. V., Deva, T.
, Andreasen, M., Valnickova, Z., Sørensen, C. S., Karring, H.
, Thøgersen, I. B., Christiansen, G., Underhaug, J., Kristensen, T.
, Nielsen, N. C., Klintworth, G. K.
, Otzen, D. E. & Enghild, J. J. (2011).
Human Phenotypically Distinct TGFBI Corneal Dystrophies Are Linked to the Stability of the Fourth FAS1 Domain of TGFBIp.
Journal of Biological Chemistry,
286(7), 4951-8.
https://doi.org/10.1074/jbc.M110.181099
Bertelsen, K., Vad, B.
, Nielsen, E. H. T., Hansen, S. K.
, Skrydstrup, T., Otzen, D., Vosegaard, T. & Nielsen, N. C. (2011).
Long-term-stable ether-lipid vs conventional ester-lipid bicelles in oriented solid-state NMR: altered structural information in studies of antimicrobial peptides.
Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical,
115(8), 1767-1774.
https://doi.org/10.1021/jp110866g
Macchi, F.
, Hoffmann, S. V., Carlsen, M., Vad, B. S.
, Imparato, A., Rischel, C.
& Otzen, D. (2011).
Mechanical stress affects glucagon fibrillation kinetics and fibril structure.
Langmuir,
27(20), 12539–12549.
https://doi.org/10.1021/la202125c
Basaiawmoit, R. V., Oliveira, C. L. P., Runager, K., Sørensen, C. S., Behrens, M. A., Jonsson, B.-H., Kristensen, T., Klintworth, G. K.
, Enghild, J. J., Pedersen, J. S. & Otzen, D. E. (2011).
SAXS models of TGFBIp reveal a trimeric structure and show that the overall shape is not affected by the Arg124His mutation.
Journal of Molecular Biology,
408(3), 503-513.
https://doi.org/10.1016/j.jmb.2011.02.052
Weber, M., Schneider, D., Prodöhl, A., Dreher, C., Becker, C., Underhaug, J., Svane, A. S. P., Malmendal, A.
, Nielsen, N. C. & Otzen, D. (2011).
SDS-facilitated in vitro formation of a transmembrane B-type cytochrome is mediated by changes in local pH.
Journal of Molecular Biology,
407(4), 594-606.
https://doi.org/10.1016/j.jmb.2011.02.005
Wang, J., Jensen, U. B., Jensen, G. V., Shipovskov, S., Balakrishnan, V. S.
, Otzen, D., Pedersen, J. S., Besenbacher, F. & Sutherland, D. S. (2011).
Soft Interactions at Nanoparticles Alter Protein Function and Conformation in a Size Dependent Manner.
Nano Letters,
11(11), 4985-4991.
https://doi.org/10.1021/nl202940k
Giehm, L., Dal Degan, F., Fraser, P., Klysner, S.
& Otzen, D. E. (2010).
An Aß concatemer with altered aggregation propensities.
BBA General Subjects,
1804(10), 2025-35.
https://doi.org/10.1016/j.bbapap.2010.06.023
Jeppesen, M. D., Hein, K.
, Nissen, P., Westh, P.
& Otzen, D. E. (2010).
A thermodynamic analysis of fibrillar polymorphism.
Advances in Biophysical Chemistry,
149(1-2), 40-6.
https://doi.org/10.1016/j.bpc.2010.03.016
Nielsen, S. B., Franzmann, M.
, Basaiawmoit, R. V., Wimmer, R., Mikkelsen, J. D.
& Otzen, D. E. (2010).
beta-Sheet aggregation of kisspeptin-10 is stimulated by heparin but inhibited by amphiphiles.
Biopolymers,
93(8), 678-89.
https://doi.org/10.1002/bip.21434
Hein, K. L.
, Kragh-Hansen, U., Morth, J. P., Jeppesen, M.
, Otzen, D., Møller, J. V.
& Nissen, P. (2010).
Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
Journal of Structural Biology,
171, 353-360.
Hjørringgaard, C. U., Vad, B., Nielsen, S. B.
, Matchkov, V., Vosegaard, T., Nielsen, N. C., Otzen, D. & Skrydstrup, T. (2010).
Cyclodextrin scaffolded alamethicin with highly efficient channel-forming properties.
Journal of Peptide Science,
16, 148.
Hjørringgaard, C. U., Vad, B. S.
, Matchkov, V., Nielsen, S. B.
, Vosegaard, T., Nielsen, N. C., Otzen, D. & Skrydstrup, T. (2010).
Cyclodextrin Scaffolded Alamethicin with Highly Efficient Channel-forming Properties. Poster session presented at 31st European Peptide Symposium, 31EPS, Copenhagen, Denmark.
Vad, B. S., Thomsen, L. A. H., Bertelsen, K., Franzmann, M., Pedersen, J. M., Nielsen, S. B.
, Vosegaard, T., Valnickova, Z.
, Skrydstrup, T., Enghild, J. J., Wimmer, R.
, Nielsen, N. C. & Otzen, D. (2010).
Divorcing folding from function: how acylation affects the membrane-perturbing properties of an antimicrobial peptide.
B B A - Proteins and Proteomics,
1804(4), 806-20.
https://doi.org/10.1016/j.bbapap.2009.12.006
Valnickova, Z., Sanglas, L., Arolas, J. L.
, Petersen, S. V., Schar, C.
, Otzen, D., Aviles, F. X., Gomis-Ruth, F. X.
& Enghild, J. J. (2010).
Flexibility of the thrombin-activatable fibrinolysis inhibitor pro-domain enables productive binding of protein substrates.
Journal of Biological Chemistry.
https://doi.org/10.1074/jbc.M110.150342
Dueholm, M. S.
, Petersen, S. V., Sønderkær, M., Larsen, P., Christiansen, G., Hein, K. L.
, Enghild, J. J., Nielsen, J. L., Nielsen, K. L., Nielsen, P. H.
& Otzen, D. E. (2010).
Functional amyloid in Pseudomonas.
Molecular Microbiology.
https://doi.org/10.1111/j.1365-2958.2010.07269.x
Andersen, C. B., Hicks, M. R., Vetri, V., Vandahl, B., Rahbek-Nielsen, H., Thøgersen, H.
, Thøgersen, I., Enghild, J. J., Serpell, L. C., Rischel, C.
& Otzen, D. E. (2010).
Glucagon fibril polymorphism reflects differences in protofilament backbone structure.
Journal of Molecular Biology,
397(4), 932-46.
https://doi.org/10.1016/j.jmb.2010.02.012
Dorosz, J., Gofman, Y., Kolusheva, S.
, Otzen, D., Ben-Tal, N.
, Nielsen, N. C. & Jelinek, R. (2010).
Membrane Interactions of Novicidin, a Novel Antimicrobial Peptide: Phosphatidylglycerol Promotes Bilayer Insertion.
Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical,
114(34), 11053-60.
https://doi.org/10.1021/jp1052248
Triano, I., Barrera, F. N., Renart, M. L., Molina, M. L., Fernández-Ballester, G., Poveda, J. A., Fernández, A. M., Encinar, J. A., Ferrer-Montiel, A. V.
, Otzen, D. & González-Ros, J. M. (2010).
Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein.
Biochemistry,
49(25), 5397-5404.
https://doi.org/10.1021/bi1003712
Vad, B. S., Bertelsen, K., Johansen, C. H., Pedersen, J. M.
, Skrydstrup, T., Nielsen, N. C. & Otzen, D. E. (2010).
Pardaxin permeabilizes vesicles more efficiently by pore formation than by disruption.
Biophysical Journal,
98(4), 576-85.
https://doi.org/10.1016/j.bpj.2009.08.063
Giehm, L., Oliveira, C. L. P. D., Christiansen, G.
, Pedersen, J. S. & Otzen, D. (2010).
SDS-Induced Fibrillation of α-Synuclein: An Alternative Fibrillation Pathway.
Journal of Molecular Biology,
401, 115-133.
https://doi.org/10.1016/j.jmb.2010.05.060