The Biomodelling group studies the interactions and dynamics of proteins and other biomolecules by use of computational chemistry, bioinformatics and molecular modelling tools. The overall goals of these studies are to observe interactions and dynamics on an atomistic level unachievable by experimentally observation. This makes it possible to identify reaction mechanisms and dynamic properties, which can be used to elucidate experimental results and for developing new, or improve existing, drugs and enzymes.
Most of the research projects in the group are interdisciplinary studies done in collaboration with experimental research groups (through PUMPKIN and inSPIN) as well as industries like Novozymes A/S and Chr. Hansen A/S.
Examples of on-going research project are studies of fibrils related to neurodegenerative diseases like Alzheimer’s and Parkinson’s diseases, membrane transporters, ion pumps, antimicrobial peptides and proteases as well as computational method development.
Our homepage can be found here